中外医疗
中外醫療
중외의료
China Foreign Medical Treatment
2015年
29期
139-141
,共3页
静脉%丙种球蛋白%甲泼尼龙%麻疹%重症肺炎
靜脈%丙種毬蛋白%甲潑尼龍%痳疹%重癥肺炎
정맥%병충구단백%갑발니룡%마진%중증폐염
Vein%Immunoglobulin%Methylprednisolone%Measles%Severe pneumonia
目的：探讨静脉丙种球蛋白联合甲泼尼龙治疗麻疹合并重症肺炎的临床疗效。方法整群选取该院2012年12月—2014年12月收治的麻疹合并重症肺炎患儿94例，按照编号随机分成观察组（n=47）和对照组（n=47），对照组采取静脉丙种球蛋白治疗，观察组则加用甲泼尼龙，比较两组临床疗效。结果观察组呼吸困难恢复时间、肺部啰音消失时间、血气恢复时间、胸片显示明显吸收时间、退热时间均短于对照组，差异有统计学意义（P＜0.05）。观察组机械通气使用率0.00%，死亡率2.13%，对照组机械通气使用率10.64%，死亡率19.15%，观察组机械通气使用率及死亡率均低于对照组，差异有统计学意义（P＜0.05）。观察组痊愈率97.87%，对照组痊愈率80.85%，观察组痊愈率高于对照组，差异有统计学意义（P＜0.05）。观察组患儿在治疗过程中，不良反应发生率0.00%；对照组患儿在治疗过程中，不良反应发生率2.13%，两组不良反应发生率比较，差异无统计学意义（P＞0.05）。结论静脉丙种球蛋白联合甲泼尼龙治疗麻疹合并重症肺炎的临床效果较单独丙种球蛋白注射更好，且较为安全，临床价值较高。
目的：探討靜脈丙種毬蛋白聯閤甲潑尼龍治療痳疹閤併重癥肺炎的臨床療效。方法整群選取該院2012年12月—2014年12月收治的痳疹閤併重癥肺炎患兒94例，按照編號隨機分成觀察組（n=47）和對照組（n=47），對照組採取靜脈丙種毬蛋白治療，觀察組則加用甲潑尼龍，比較兩組臨床療效。結果觀察組呼吸睏難恢複時間、肺部啰音消失時間、血氣恢複時間、胸片顯示明顯吸收時間、退熱時間均短于對照組，差異有統計學意義（P＜0.05）。觀察組機械通氣使用率0.00%，死亡率2.13%，對照組機械通氣使用率10.64%，死亡率19.15%，觀察組機械通氣使用率及死亡率均低于對照組，差異有統計學意義（P＜0.05）。觀察組痊愈率97.87%，對照組痊愈率80.85%，觀察組痊愈率高于對照組，差異有統計學意義（P＜0.05）。觀察組患兒在治療過程中，不良反應髮生率0.00%；對照組患兒在治療過程中，不良反應髮生率2.13%，兩組不良反應髮生率比較，差異無統計學意義（P＞0.05）。結論靜脈丙種毬蛋白聯閤甲潑尼龍治療痳疹閤併重癥肺炎的臨床效果較單獨丙種毬蛋白註射更好，且較為安全，臨床價值較高。
목적：탐토정맥병충구단백연합갑발니룡치료마진합병중증폐염적림상료효。방법정군선취해원2012년12월—2014년12월수치적마진합병중증폐염환인94례，안조편호수궤분성관찰조（n=47）화대조조（n=47），대조조채취정맥병충구단백치료，관찰조칙가용갑발니룡，비교량조림상료효。결과관찰조호흡곤난회복시간、폐부라음소실시간、혈기회복시간、흉편현시명현흡수시간、퇴열시간균단우대조조，차이유통계학의의（P＜0.05）。관찰조궤계통기사용솔0.00%，사망솔2.13%，대조조궤계통기사용솔10.64%，사망솔19.15%，관찰조궤계통기사용솔급사망솔균저우대조조，차이유통계학의의（P＜0.05）。관찰조전유솔97.87%，대조조전유솔80.85%，관찰조전유솔고우대조조，차이유통계학의의（P＜0.05）。관찰조환인재치료과정중，불량반응발생솔0.00%；대조조환인재치료과정중，불량반응발생솔2.13%，량조불량반응발생솔비교，차이무통계학의의（P＞0.05）。결론정맥병충구단백연합갑발니룡치료마진합병중증폐염적림상효과교단독병충구단백주사경호，차교위안전，림상개치교고。
Objective To observe the clinical curative effect of intravenous gamma globulin combined with methylprednisolone in the treatment of measles complicated with severe pneumonia. Methods Select our hospital supplementary information to select the starting and ending date 2012-12/2014-12 were measles combined with severe pneumonia in 94 cases, according to numbers were randomly divided into observation group (n=47) and control group (n=47), control group was treated with intravenous immunoglobulin therapy, observation group were treated with methylprednisolone, compared two groups of clinical curative effect. Results For the observation group, the time period for difficulty breathing recovery, pulmonary rales disappear, blood gas recovery, chest-X-ray-showed absorption, and cooling were shorter than those of the control group, with statistically significant differences(P<0.05). Mechanical ventilation rate and mortality rate of the observation group were 0.00% and 2.13%, while those of the control group were 10.64% and 19.15%, with statistically significant differences between groups (P<0.05). The difference of incidences of adverse reactions between the treatment of the observation group (0.00%) and the control group (2.13%) were not statistically significant (P>0.05). Conclusion Clinical effect of intravenous injection of gamma globulin combined with methylprednisolone in treating measles complicated with severe pneumonia treatment is better than single injection of gamma globulin. It is safe and of high clinical value.
