CAJ | 학술논문

目的：研究阿仑膦酸钠片联合骨肽片治疗骨质疏松症伴疼痛的临床效果。方法整群选取2014年1月—2015年1月收治骨质疏松症伴疼痛患者110例，随机分为观察组（n=55）和对照组（n=55），对照组给予阿仑膦酸钠片口服治疗；观察组在此基础上加用骨肽片饭后口服，观察两组治疗效果及不良反应。结果观察组治疗后总有效率89.1%显著高于对照组74.5%（χ2=3.91，P<0.05）；两组患者不良反应发生率对比差异无统计学意义（χ2=2.95，P>0.05）。结论阿仑膦酸钠片联合骨肽片治疗骨质疏松症伴疼痛疗效好，患者疼痛症状改善快，值得推广。
목적：연구아륜련산납편연합골태편치료골질소송증반동통적림상효과。방법정군선취2014년1월—2015년1월수치골질소송증반동통환자110례，수궤분위관찰조（n=55）화대조조（n=55），대조조급여아륜련산납편구복치료；관찰조재차기출상가용골태편반후구복，관찰량조치료효과급불량반응。결과관찰조치료후총유효솔89.1%현저고우대조조74.5%（χ2=3.91，P<0.05）；량조환자불량반응발생솔대비차이무통계학의의（χ2=2.95，P>0.05）。결론아륜련산납편연합골태편치료골질소송증반동통료효호，환자동통증상개선쾌，치득추엄。
Objective To study the clinical effect of alendronate sodium tablets combined with ossotide tablets in the treat-ment of osteoporosis with pain. Methods 110 cases of patients having osteoporosis with pain admitted from January 2014 to January 2015 were selected and randomly divided into the observation group(55 cases) and the control group(n=55). The control group was given alendronate sodium tablets for treatment while the observation group received oral administration of ossotide tablets after meal based on the treatment of the control group. The curative effect and adverse reactions in the two groups were observed. Results In the observation group, the total efficiency was 89.1% which was significantly higher than 74.5%of the control group (χ2=3.91, P<0.05);The comparison of incidence of adverse reactions in the two groups of patients was of no significant difference and no statistical significance(χ2=2.95, P>0.05). Conclusion The curative effect of alendronate sodium tablets combined with ossotide tablets in the treatment of osteoporosis with pain is good with which the pain symptoms of patients are improved quickly, which is worthy to be popularized.