中国中医药信息杂志
中國中醫藥信息雜誌
중국중의약신식잡지
Chinese Journal of Information on Traditional Chinese Medicine
2015年
11期
24-28
,共5页
通痹舒心颗粒%急性冠脉综合征伴焦虑抑郁%中西医结合疗法
通痺舒心顆粒%急性冠脈綜閤徵伴焦慮抑鬱%中西醫結閤療法
통비서심과립%급성관맥종합정반초필억욱%중서의결합요법
Tongbi Shuxin Granule%acute coronary syndrome with anxiety and depression%integrated traditional Chinese and Western medicine therapy
目的 观察通痹舒心颗粒对急性冠脉综合征(ACS)伴焦虑抑郁患者生活质量的影响.方法 采用随机数字表法将90例患者分为治疗组和对照组各45例.对照组予基础治疗并进行情志干预,治疗组在对照组治疗基础上加服通痹舒心颗粒.分别于治疗前及治疗第 4、12 周采用汉密顿焦虑量表(HAMA)和抑郁量表(HAMD)进行评分,在治疗前及治疗第12周进行西雅图心绞痛量表(SAQ)评分,比较2组变化情况.结果 2组患者治疗第4周时HAMD、HAMA评分与本组治疗前比较均降低,差异有统计学意义(P<0.05),组间比较差异也有统计学意义(P<0.05).治疗第12周时,对照组HAMD、HAMA评分较第4周时略有降低(P>0.05),治疗组较治疗前及治疗第4周时明显下降(P<0.05),组间比较差异有统计学意义(P<0.05).2组患者治疗第12周时SAQ评分所有维度较治疗前均提高(P<0.05),治疗组评分较对照组提高更明显,其中躯体活动受限程度、心绞痛稳定状态和心绞痛发作情况评分与对照组比较差异有统计学意义(P<0.05).结论 通痹舒心颗粒治疗ACS伴焦虑抑郁患者有明显疗效.
目的 觀察通痺舒心顆粒對急性冠脈綜閤徵(ACS)伴焦慮抑鬱患者生活質量的影響.方法 採用隨機數字錶法將90例患者分為治療組和對照組各45例.對照組予基礎治療併進行情誌榦預,治療組在對照組治療基礎上加服通痺舒心顆粒.分彆于治療前及治療第 4、12 週採用漢密頓焦慮量錶(HAMA)和抑鬱量錶(HAMD)進行評分,在治療前及治療第12週進行西雅圖心絞痛量錶(SAQ)評分,比較2組變化情況.結果 2組患者治療第4週時HAMD、HAMA評分與本組治療前比較均降低,差異有統計學意義(P<0.05),組間比較差異也有統計學意義(P<0.05).治療第12週時,對照組HAMD、HAMA評分較第4週時略有降低(P>0.05),治療組較治療前及治療第4週時明顯下降(P<0.05),組間比較差異有統計學意義(P<0.05).2組患者治療第12週時SAQ評分所有維度較治療前均提高(P<0.05),治療組評分較對照組提高更明顯,其中軀體活動受限程度、心絞痛穩定狀態和心絞痛髮作情況評分與對照組比較差異有統計學意義(P<0.05).結論 通痺舒心顆粒治療ACS伴焦慮抑鬱患者有明顯療效.
목적 관찰통비서심과립대급성관맥종합정(ACS)반초필억욱환자생활질량적영향.방법 채용수궤수자표법장90례환자분위치료조화대조조각45례.대조조여기출치료병진행정지간예,치료조재대조조치료기출상가복통비서심과립.분별우치료전급치료제 4、12 주채용한밀돈초필량표(HAMA)화억욱량표(HAMD)진행평분,재치료전급치료제12주진행서아도심교통량표(SAQ)평분,비교2조변화정황.결과 2조환자치료제4주시HAMD、HAMA평분여본조치료전비교균강저,차이유통계학의의(P<0.05),조간비교차이야유통계학의의(P<0.05).치료제12주시,대조조HAMD、HAMA평분교제4주시략유강저(P>0.05),치료조교치료전급치료제4주시명현하강(P<0.05),조간비교차이유통계학의의(P<0.05).2조환자치료제12주시SAQ평분소유유도교치료전균제고(P<0.05),치료조평분교대조조제고경명현,기중구체활동수한정도、심교통은정상태화심교통발작정황평분여대조조비교차이유통계학의의(P<0.05).결론 통비서심과립치료ACS반초필억욱환자유명현료효.
Objective To observe the effects of Tongbi Shuxin Granule on life quality of acute coronary syndrome (ACS) patients with anxiety and depression.Methods Ninety patients were randomly divided into the treatment group and control group through random number table method, 45 cases for each group. The control group was given fundamental treatment and emotional intervention, while the treatment group was given Tongbi Shuxin Granule additionally. On admission and 4th and 12th weeks, the scores of HAMA and HAMD were evaluated. On admission and 12th week, SAQ score was observed.Results In the 4th week, scores of HAMD and HAMA of two groups decreased compared with those on admission (P<0.05), with statistical significance (P<0.05). In the 12th week, scores of HAMD and HAMA of the control group were lower than those of 4th week, without statistical significance (P>0.05);the treatment group decreased significantly compared with on admission and 4th week (P<0.05), without statistical significance between the two groups (P<0.05). In the 12th week, all dimensions of SAQ score in the two groups increased compared with those on admission (P<0.05);the treatment group was much higher than the control group, especially the scores of physical limitation, angina stability and angina frequency (P<0.05).Conclusion Tongbi Shuxin Granule has the exact treatment effects on ACS patients with anxiety and depression.
