中国中医药信息杂志
中國中醫藥信息雜誌
중국중의약신식잡지
Chinese Journal of Information on Traditional Chinese Medicine
2015年
11期
62-64
,共3页
赵慧巧%张艳霞%刘雪枫%陈正君%卢年华%景明
趙慧巧%張豔霞%劉雪楓%陳正君%盧年華%景明
조혜교%장염하%류설풍%진정군%로년화%경명
湿生扁蕾%苦豆子%镇痛%抗炎%小鼠
濕生扁蕾%苦豆子%鎮痛%抗炎%小鼠
습생편뢰%고두자%진통%항염%소서
Gentianopsis Paludosa%Sophora Alopecuroide%analgesic effect%anti-inflammatory effect%mice
目的 比较湿生扁蕾与苦豆子不同比例配伍对小鼠的镇痛、抗炎作用.方法 将小鼠随机分为正常组、阳性药组、不同配伍组,每组10只,连续灌胃7 d,每日1次.采用冰醋酸扭体法和热板致痛法比较不同配伍的镇痛作用,采用二甲苯致小鼠耳肿胀法和琼脂致肉芽肿法比较不同配伍的抗炎作用.结果 与正常组比较,湿生扁蕾复方镇痛、抗炎作用明显(P<0.01),湿生扁蕾和苦豆子按20:0.6和20:0.9配伍时,镇痛、抗炎效果较好.结论 湿生扁蕾-苦豆子配伍具有较好的镇痛、抗炎作用,以湿生扁蕾和苦豆子20:0.6配伍最佳.
目的 比較濕生扁蕾與苦豆子不同比例配伍對小鼠的鎮痛、抗炎作用.方法 將小鼠隨機分為正常組、暘性藥組、不同配伍組,每組10隻,連續灌胃7 d,每日1次.採用冰醋痠扭體法和熱闆緻痛法比較不同配伍的鎮痛作用,採用二甲苯緻小鼠耳腫脹法和瓊脂緻肉芽腫法比較不同配伍的抗炎作用.結果 與正常組比較,濕生扁蕾複方鎮痛、抗炎作用明顯(P<0.01),濕生扁蕾和苦豆子按20:0.6和20:0.9配伍時,鎮痛、抗炎效果較好.結論 濕生扁蕾-苦豆子配伍具有較好的鎮痛、抗炎作用,以濕生扁蕾和苦豆子20:0.6配伍最佳.
목적 비교습생편뢰여고두자불동비례배오대소서적진통、항염작용.방법 장소서수궤분위정상조、양성약조、불동배오조,매조10지,련속관위7 d,매일1차.채용빙작산뉴체법화열판치통법비교불동배오적진통작용,채용이갑분치소서이종창법화경지치육아종법비교불동배오적항염작용.결과 여정상조비교,습생편뢰복방진통、항염작용명현(P<0.01),습생편뢰화고두자안20:0.6화20:0.9배오시,진통、항염효과교호.결론 습생편뢰-고두자배오구유교호적진통、항염작용,이습생편뢰화고두자20:0.6배오최가.
Objective To compare analgesic and anti-inflammatory effects of Gentianopsis Paludosa and Sophora Alopecuroide of different kinds of compatibility on the mice.Methods Mice were randomly divided into normal control group, positive medicine group, and different kinds of compatibility groups, 10 mice in each group. Mice received gavage for successive 7 days, once a day. Glacial acetic acid twist body method and hot board to pain method were used to observe and compare analgesic effects of different kinds of compatibility. Xylene to ear swelling method and agar to granulation swollen method were used to observe and compare inflammatory effects of different kinds of compatibility.Results Compared with normal group, compound Gentianopsis Paludosa had obvious analgesic and anti-inflammatory effects (P<0.01). When the ratio of Gentianopsis Paludosa and Sophora Alopecuroide was 20:0.6 and 20:0.9, the analgesic and anti-inflammatory effects were the best.Conclusion Gentianopsis Paludosa and Sophora Alopecuroide have good analgesic and anti-inflammatory effects, among which, when the ratio of Gentianopsis Paludosa and Sophora Alopecuroide is 20:0.6, the best effects show.
