中外医疗
中外醫療
중외의료
China Foreign Medical Treatment
2015年
29期
4-6
,共3页
幽门螺杆菌%消化性溃疡%三联疗法%双歧杆菌四联活菌片
幽門螺桿菌%消化性潰瘍%三聯療法%雙歧桿菌四聯活菌片
유문라간균%소화성궤양%삼련요법%쌍기간균사련활균편
Helicobacter pylori%Peptic ulcer%Triple therapy%Bifidobacterium Tetravaccine Tablets
目的：探讨采用双歧杆菌四联活菌片联合三联疗法对幽门螺杆菌阳性消化性溃疡进行治疗的临床效果。方法随机选取该院2013年4月—2015年2月期间收治的幽门螺杆菌阳性消化性溃疡患者92例，按照治疗方法的不同将其分为对照组和观察组，其中对照组患者仅使用三联疗法进行治疗，观察组患者在三联疗法的基础上联合双歧杆菌四联活菌片进行治疗，对两组患者的临床治疗效果进行观察分析。结果观察组患者治疗结束时其Hp清除率(89.13%)、生长抑素（90.2±20.1）pg/mL 和胃动素水平（357.9±83.2）ng/mL 均明显优于对照组患者（54.35%）、（69.4±19.5）pg/mL、（439.3±70.2）ng/mL，差异有统计学意义（P<0.05）。结论采用双歧杆菌四联活菌片联合三联疗法治疗幽门螺杆菌阳性消化道溃疡，效果显著，能够有效改善患者的临床症状，建议在临床上进一步推广。
目的：探討採用雙歧桿菌四聯活菌片聯閤三聯療法對幽門螺桿菌暘性消化性潰瘍進行治療的臨床效果。方法隨機選取該院2013年4月—2015年2月期間收治的幽門螺桿菌暘性消化性潰瘍患者92例，按照治療方法的不同將其分為對照組和觀察組，其中對照組患者僅使用三聯療法進行治療，觀察組患者在三聯療法的基礎上聯閤雙歧桿菌四聯活菌片進行治療，對兩組患者的臨床治療效果進行觀察分析。結果觀察組患者治療結束時其Hp清除率(89.13%)、生長抑素（90.2±20.1）pg/mL 和胃動素水平（357.9±83.2）ng/mL 均明顯優于對照組患者（54.35%）、（69.4±19.5）pg/mL、（439.3±70.2）ng/mL，差異有統計學意義（P<0.05）。結論採用雙歧桿菌四聯活菌片聯閤三聯療法治療幽門螺桿菌暘性消化道潰瘍，效果顯著，能夠有效改善患者的臨床癥狀，建議在臨床上進一步推廣。
목적：탐토채용쌍기간균사련활균편연합삼련요법대유문라간균양성소화성궤양진행치료적림상효과。방법수궤선취해원2013년4월—2015년2월기간수치적유문라간균양성소화성궤양환자92례，안조치료방법적불동장기분위대조조화관찰조，기중대조조환자부사용삼련요법진행치료，관찰조환자재삼련요법적기출상연합쌍기간균사련활균편진행치료，대량조환자적림상치료효과진행관찰분석。결과관찰조환자치료결속시기Hp청제솔(89.13%)、생장억소（90.2±20.1）pg/mL 화위동소수평（357.9±83.2）ng/mL 균명현우우대조조환자（54.35%）、（69.4±19.5）pg/mL、（439.3±70.2）ng/mL，차이유통계학의의（P<0.05）。결론채용쌍기간균사련활균편연합삼련요법치료유문라간균양성소화도궤양，효과현저，능구유효개선환자적림상증상，건의재림상상진일보추엄。
Objective To explore the clinical effect of Bifidobacterium Tetravaccine Tablets combined with triple therapy on Helicobacter pylori positive peptic ulcer. Methods Ninety-two cases with Helicobacter pylori positive peptic ulcer admitted in our hospital from April 2013 to February 2015 were randomly selected and divided into the control group and the obser-vation group in accordance with the treatment method. Patients in the control group were treated by triple therapy, while those in the observation group were treated by triple therapy combined with Bifidobacterium Tetravaccine Tablets. And the clinical efficacy of the two groups was observed and analyzed. Results At the end of treatment, compared with the control group, the observation group had much higher Hp clearance(89.13%vs 54.35%), obviously higher somatostatin level [ (90.2± 20.1)pg/mL vs (69.4±19.5)pg/mL], significantly lower motilin level [(357.9±83.2)ng/mL vs (439.3±70.2)ng/mL] with sta-tistically significant difference (P<0.05). Conclusion For patients with Helicobacter pylori positive peptic ulcer, Bifidobac-terium Tetravaccine Tablets combined with triple therapy has significant effect, which can effectively improve the clinical symptoms of the patients, so it is recommended to be further promoted in clinical practice.
