中国全科医学
中國全科醫學
중국전과의학
Chinese General Practice
2015年
32期
3906-3909
,共4页
心脏停搏%消化系统%再灌注损伤%低温%综述
心髒停搏%消化繫統%再灌註損傷%低溫%綜述
심장정박%소화계통%재관주손상%저온%종술
Heart arrest%Digestive system%Reperfusion injury%Hypothermia%Review
目前,心搏骤停复苏患者自主循环恢复( ROSC)成功率逐渐提高,但患者最终的生存率仍然较低,心搏骤停后综合征(PCAS)或复苏后多脏器功能障碍综合征(MODS)为主要死亡原因。治疗性低温指将患者核心体温降至32~34℃,是目前唯一被证实能够提高心搏骤停患者生存率的方法。低温治疗在神经系统领域应用广泛并且成熟,但目前低温治疗对患者消化系统的受益情况仍存在争议。本文探讨了心搏骤停后消化系统损伤的病理生理机制,总结低温对胃肠道、肝脏及胰腺影响的相关研究,以期为心搏骤停后消化系统损伤的低温治疗提供借鉴。
目前,心搏驟停複囌患者自主循環恢複( ROSC)成功率逐漸提高,但患者最終的生存率仍然較低,心搏驟停後綜閤徵(PCAS)或複囌後多髒器功能障礙綜閤徵(MODS)為主要死亡原因。治療性低溫指將患者覈心體溫降至32~34℃,是目前唯一被證實能夠提高心搏驟停患者生存率的方法。低溫治療在神經繫統領域應用廣汎併且成熟,但目前低溫治療對患者消化繫統的受益情況仍存在爭議。本文探討瞭心搏驟停後消化繫統損傷的病理生理機製,總結低溫對胃腸道、肝髒及胰腺影響的相關研究,以期為心搏驟停後消化繫統損傷的低溫治療提供藉鑒。
목전,심박취정복소환자자주순배회복( ROSC)성공솔축점제고,단환자최종적생존솔잉연교저,심박취정후종합정(PCAS)혹복소후다장기공능장애종합정(MODS)위주요사망원인。치료성저온지장환자핵심체온강지32~34℃,시목전유일피증실능구제고심박취정환자생존솔적방법。저온치료재신경계통영역응용엄범병차성숙,단목전저온치료대환자소화계통적수익정황잉존재쟁의。본문탐토료심박취정후소화계통손상적병리생리궤제,총결저온대위장도、간장급이선영향적상관연구,이기위심박취정후소화계통손상적저온치료제공차감。
At present,the success rate of return of spontaneous circulation(ROSC)in patients with cardiac arrest has gradually improved,but the final survival rate of patients is still low. Post - cardiac arrest syndrome(PCAS)and multiple organ dysfunction syndrome( MODS)are the major causes of death. Therapeutic hypothermia is defined as patient' s core body temperature being down to 32 to 34 ℃ ,and it has been proven the only way to improve the survival rate of patients with cardiac arrest so far. Hypothermia has been widely used and has become mature in the field of nervous system,but the influence of hypothermia on the digestive system remains controversial. This paper discussed the pathophysiological mechanism of the digestive system injury following cardiac arrest,and made a review of the related research of the influence of hypothermia on gastrointestinal tract,liver and pancreas in order to provide references for hypothermia treatment after cardiac arrest.