CAJ | 학술논문

心搏骤停后急性肾损伤（AKI）是心搏骤停患者经有效生命支持获得自主循环恢复后常面临的重要并发症。由于其高发病率、病死率，日益受到临床医师的关注。目前，心搏骤停后肾保护措施仍然有限，复苏后休克状态可能成为临床重要的干预靶点，给予精确的液体管理有望明显减少 AKI 的发生或进一步恶化。新型肾损伤标志物有助于更早发现心搏骤停后 AKI 患者，为尽早识别和实施干预提供线索，从而改善预后。本文重点就心搏骤停后发生AKI 的病理生理机制、危险因素、干预措施及新型肾损伤标志物进行综述。
심박취정후급성신손상（AKI）시심박취정환자경유효생명지지획득자주순배회복후상면림적중요병발증。유우기고발병솔、병사솔，일익수도림상의사적관주。목전，심박취정후신보호조시잉연유한，복소후휴극상태가능성위림상중요적간예파점，급여정학적액체관리유망명현감소 AKI 적발생혹진일보악화。신형신손상표지물유조우경조발현심박취정후 AKI 환자，위진조식별화실시간예제공선색，종이개선예후。본문중점취심박취정후발생AKI 적병리생리궤제、위험인소、간예조시급신형신손상표지물진행종술。
Acute kidney injury after cardiac arrest is a significant syndrome. Cardiac arrest patients who gain resumption of spontaneous circulation by effective life support often need to face the condition. Because of its high prevalence and mortality rate,the clinicians pay increasingly more attention to it. At present,related renal protective measures are still limited. Shock after resuscitation may become an important clinical intervention target. Accurate liquid management is expected to significantly reduce the occurrence of AKI or prevent it from deteriorating. New biomarkers of kidney injury help to detect AKI earlier after cardiac arrest,and may provide clues for early identification and intervention,so as to improve the prognosis. The paper made a review of the physiopathologic mechanism,risk factors and intervention measures of AKI after heart arrest.