CAJ | 학술논문

自身免疫性多内分泌腺病综合征（ APS）是指以2个或2个以上的内分泌腺体因自身免疫功能缺陷而发生功能受损为主要表现的一系列综合征，亦可累及非内分泌腺器官。本文报道了1例APS-4型患者先后出现脱毛症、溃疡性结肠炎、1型糖尿病、促肾上腺皮质激素（ ACTH）缺乏型腺垂体功能减退。APS-4型是一种少见的综合征，常伴有多种内分泌腺功能减退，要注意补充一种激素的同时可能影响另一种疾病的治疗。
자신면역성다내분비선병종합정（ APS）시지이2개혹2개이상적내분비선체인자신면역공능결함이발생공능수손위주요표현적일계렬종합정，역가루급비내분비선기관。본문보도료1례APS-4형환자선후출현탈모증、궤양성결장염、1형당뇨병、촉신상선피질격소（ ACTH）결핍형선수체공능감퇴。APS-4형시일충소견적종합정，상반유다충내분비선공능감퇴，요주의보충일충격소적동시가능영향령일충질병적치료。
Autoimmune polyendocrine syndrome(APS)refers to the dysfunction of two or more endocrine glandsdue to the deficiency of autoimmune function,also involving non-endocrine organs. The paper reported a case of APS-4 patient who had alopecia,ulcerative colitis,type 1 diabetes mellitus and ACTH-deficient hypopituitarism successively. APS-4 type is a rare syndrome concurrent with multiple kinds of hypopituitarism. Attention should be given that the supplement of one hormone may affect the treatment of another disease.