中国全科医学
中國全科醫學
중국전과의학
Chinese General Practice
2015年
32期
3936-3938,3943
,共4页
莫为春%张志华%郑凤雅%张熙%申捷
莫為春%張誌華%鄭鳳雅%張熙%申捷
막위춘%장지화%정봉아%장희%신첩
肺疾病,慢性阻塞性%二维斑点追踪成像%心室功能,右%高血压,肺性
肺疾病,慢性阻塞性%二維斑點追蹤成像%心室功能,右%高血壓,肺性
폐질병,만성조새성%이유반점추종성상%심실공능,우%고혈압,폐성
Pulmonary disease,chronic obstructive%Two - dimensional speckled tracking imaging%Ventricular function,right%Hypertension pulmonary
目的:探讨二维斑点追踪技术(2D - STI)评估肺动脉压正常的慢性阻塞性肺疾病(COPD)患者右心室功能损害的价值。方法选取2012年4月—2013年4月于复旦大学附属金山医院治疗的肺动脉压正常的稳定期COPD 患者60例(COPD 组),另选取本院体检健康者40例为对照组。收集受试者性别、年龄、基础心率、体表面积等临床资料,记录心血管疾病史。采用 GE Vivid 7超声诊断仪采集受试者平静呼吸时3个心动周期心尖四腔二维动态影像,记录常规超声参数。将动态影像导入 Echo PAC 工作站,应用2D - STI 分析软件进行脱机分析,记录右心室游离壁基底部、中间部、心尖部及整体长轴应变。结果两组左心室射血分数(LVEF)、肺动脉收缩压(PASP)、右心室舒张期内径(RVDd)、右心室收缩期内径(RVDs)、右心室射血分数(RVEF)、右心室面积变化分数( RVFAC)、E峰、E/ A 比值、E 峰减速时间(DT)、右房室瓣环运动速度(e')、E/ e'及右心室 Tei 指数比较,差异均无统计学意义(P ﹥0.05)。而两组右心室壁厚度(RVWH)和 A 峰比较,差异有统计学意义(P ﹤0.05)。COPD 组右心室游离壁基底部、中间部、心尖部及整体长轴应变功能均低于对照组,差异有统计学意义( P ﹤0.05)。结论肺动脉压正常的COPD 患者右心室长轴应变功能已经开始减弱,2D - STI 可早期发现其右心室功能的轻微改变。
目的:探討二維斑點追蹤技術(2D - STI)評估肺動脈壓正常的慢性阻塞性肺疾病(COPD)患者右心室功能損害的價值。方法選取2012年4月—2013年4月于複旦大學附屬金山醫院治療的肺動脈壓正常的穩定期COPD 患者60例(COPD 組),另選取本院體檢健康者40例為對照組。收集受試者性彆、年齡、基礎心率、體錶麵積等臨床資料,記錄心血管疾病史。採用 GE Vivid 7超聲診斷儀採集受試者平靜呼吸時3箇心動週期心尖四腔二維動態影像,記錄常規超聲參數。將動態影像導入 Echo PAC 工作站,應用2D - STI 分析軟件進行脫機分析,記錄右心室遊離壁基底部、中間部、心尖部及整體長軸應變。結果兩組左心室射血分數(LVEF)、肺動脈收縮壓(PASP)、右心室舒張期內徑(RVDd)、右心室收縮期內徑(RVDs)、右心室射血分數(RVEF)、右心室麵積變化分數( RVFAC)、E峰、E/ A 比值、E 峰減速時間(DT)、右房室瓣環運動速度(e')、E/ e'及右心室 Tei 指數比較,差異均無統計學意義(P ﹥0.05)。而兩組右心室壁厚度(RVWH)和 A 峰比較,差異有統計學意義(P ﹤0.05)。COPD 組右心室遊離壁基底部、中間部、心尖部及整體長軸應變功能均低于對照組,差異有統計學意義( P ﹤0.05)。結論肺動脈壓正常的COPD 患者右心室長軸應變功能已經開始減弱,2D - STI 可早期髮現其右心室功能的輕微改變。
목적:탐토이유반점추종기술(2D - STI)평고폐동맥압정상적만성조새성폐질병(COPD)환자우심실공능손해적개치。방법선취2012년4월—2013년4월우복단대학부속금산의원치료적폐동맥압정상적은정기COPD 환자60례(COPD 조),령선취본원체검건강자40례위대조조。수집수시자성별、년령、기출심솔、체표면적등림상자료,기록심혈관질병사。채용 GE Vivid 7초성진단의채집수시자평정호흡시3개심동주기심첨사강이유동태영상,기록상규초성삼수。장동태영상도입 Echo PAC 공작참,응용2D - STI 분석연건진행탈궤분석,기록우심실유리벽기저부、중간부、심첨부급정체장축응변。결과량조좌심실사혈분수(LVEF)、폐동맥수축압(PASP)、우심실서장기내경(RVDd)、우심실수축기내경(RVDs)、우심실사혈분수(RVEF)、우심실면적변화분수( RVFAC)、E봉、E/ A 비치、E 봉감속시간(DT)、우방실판배운동속도(e')、E/ e'급우심실 Tei 지수비교,차이균무통계학의의(P ﹥0.05)。이량조우심실벽후도(RVWH)화 A 봉비교,차이유통계학의의(P ﹤0.05)。COPD 조우심실유리벽기저부、중간부、심첨부급정체장축응변공능균저우대조조,차이유통계학의의( P ﹤0.05)。결론폐동맥압정상적COPD 환자우심실장축응변공능이경개시감약,2D - STI 가조기발현기우심실공능적경미개변。
Objective To investigate the value of two - dimensional speckle tracking imaging(2D - STI)in the assessment of right ventricular myocardial function impairment in patients with chronic obstructive pulmonary disease(COPD)and normal pulmonary artery pressure. Methods We enrolled 60 COPD patients in stable phrase and with normal pulmonary artery pressure who received treatment in Jinshan Hospital,Fudan University from April 2012 to April 2013 as COPD group,and we enrolled another 40 healther from this hospital as control group. We collected clinical data of the subjects,such as gender,age, basic heart rate and body surface area,and recorded the history of cardiovascular disease. GE Vivid 7 diasonograph was used to obtain the two - dimensional dynamic images of apical four chamber for three cardiac cycles when the subjects were in eupnoea, and the conventional ultrasound parameters were recorded. The dynamic images were imported into Echo PAC,and offline analysis was conducted using 2D - STI analysis software;meantime,the right ventricular longitudinal strains( LS)of basal,middle, apical and whole levels were measured. Results The two groups were not significantly different(P ﹥ 0. 05)in LVEF,PASP, RVDd,RVDs,RVEF,RVFAC,E peak,E/ A,DT,e'、E/ e' and Tei index of right ventricle. The two groups were significantly different( P ﹤ 0. 05)in RVWH and A peak. COPD group was lower( P ﹤ 0. 05)than control group in right ventricular LS of basal,middle,apical and global levels. Conclusion COPD patients with normal pulmonary artery pressure already have impaired right ventricular function. The slight changes of right ventricular myocardial function could be detected in the early stage of COPD by 2D - STI.