CAJ | 학술논문

目的：探讨增强型体外反搏治疗进展性缺血性卒中的临床疗效及其对神经功能的影响。方法选取2013年11月—2015年5月广东省深圳市第四人民医院神经内科诊治的进展性缺血性卒中患者80例，根据随机数字表法分为治疗组和对照组，各40例。对照组患者给予常规治疗，治疗组患者在对照组基础上给予增强型体外反搏治疗，两组患者治疗疗程均为1个月。比较两组患者临床疗效，治疗前后美国国立卫生研究院卒中量表（ NIHSS）评分、Rankin 评分及肱动脉超声检查指标〔肱动脉血流介导的内皮依赖性舒张功能（ FMD）及非内皮依赖性舒张功能（NMD）〕。结果治疗组患者临床疗效优于对照组（P <0.05）。治疗前两组患者 NIHSS 评分和 Rankin 评分比较，差异无统计学意义（P >0.05）；治疗后治疗组患者 NIHSS 评分和 Rankin 评分低于对照组（ P <0.05）。治疗前两组患者FMD 和 NMD 比较，差异无统计学意义（P >0.05）；治疗后治疗组患者 FMD 和 NMD 高于对照组（P <0.05）。结论增强型体外反搏治疗进展性缺血性卒中的临床疗效确切，能有效改善患者神经功能。
목적：탐토증강형체외반박치료진전성결혈성졸중적림상료효급기대신경공능적영향。방법선취2013년11월—2015년5월광동성심수시제사인민의원신경내과진치적진전성결혈성졸중환자80례，근거수궤수자표법분위치료조화대조조，각40례。대조조환자급여상규치료，치료조환자재대조조기출상급여증강형체외반박치료，량조환자치료료정균위1개월。비교량조환자림상료효，치료전후미국국립위생연구원졸중량표（ NIHSS）평분、Rankin 평분급굉동맥초성검사지표〔굉동맥혈류개도적내피의뢰성서장공능（ FMD）급비내피의뢰성서장공능（NMD）〕。결과치료조환자림상료효우우대조조（P <0.05）。치료전량조환자 NIHSS 평분화 Rankin 평분비교，차이무통계학의의（P >0.05）；치료후치료조환자 NIHSS 평분화 Rankin 평분저우대조조（ P <0.05）。치료전량조환자FMD 화 NMD 비교，차이무통계학의의（P >0.05）；치료후치료조환자 FMD 화 NMD 고우대조조（P <0.05）。결론증강형체외반박치료진전성결혈성졸중적림상료효학절，능유효개선환자신경공능。
Objective To investigate the clinical effect of enhanced external counterpulsation on progressive ischemic stroke and its impact on neurological function. Methods From November 2013 to May 2015,a total of 80 patients with progressive ischemic stroke were selected in the Department of Neurology,the Fourth People's Hospital of Shenzhen,and they were divided into control group and treatment group according to random number table. Patients of control group received conventional treatment,while patients of treatment group received extra enhanced external counterpulsation;both groups treated for one month. Clinical effect,NIHSS score,Rankin score,flow - mediated vasodilation(FMD)and nitroglycerin - mediated dilation(NMD)before and after treatment were compared between the two groups. Results The clinical effect of treatment group was statistically significantly better than that of control group(P < 0. 05). No statistically significant differences of NIHSS score or Rankin score was found between the two groups before treatment(P > 0. 05),while NIHSS score and Rankin score of treatment group were statistically significantly lower than those of control group after treatment( P < 0. 05). No statistically significant differences of FMD or NMD was found between the two groups before treatment(P > 0. 05),while FMD and NMD of treatment group were statistically significantly higher than those of control group after treatment( P < 0. 05). Conclusion Enhanced external counterpulsation has certain clinical effect in treating progressive ischemic stroke,can effectively improve the neurological function.