当代医学
噹代醫學
당대의학
Contemporary Medicine
2015年
31期
5-8
,共4页
乳管镜%乳头溢液%乳腺癌
乳管鏡%乳頭溢液%乳腺癌
유관경%유두일액%유선암
Mammaryfiberoptic ductoscopy%Nipple discharge%Breast cancer
目的:探讨纤维乳管镜在自发性乳头溢液病因诊断中的效果。方法回顾性分析行乳管镜检查的828例自发性乳头溢液患者的临床资料并结合最新的文献资料。结果在乳头溢液疾病检查中,乳管镜的敏感性和特异性分别为96.4%(798/828)和97.1%(435/448);乳头溢液中血性溢液发生率最高58.2%(482/828),引起乳头溢液疾病中乳管乳头状瘤发病率最高55.1%(456/828),乳腺癌发病率是7.0%(58/828),其中86.2%(50/58)的是原位癌;乳管内肿瘤疾病以血性的乳头溢液为主,发生率是67.8%(472/696);乳管内非肿瘤性疾病中以浆液性、乳汁性、水性的乳头溢液为主,发生率90.2%(92/102)(P=0.001)。FDS的副损伤及并发症发生率7.9%,无严重并发症及死亡病例。结论纤维乳管镜在乳头溢液疾病的诊断中敏感性、特异性均较高,而且简便易行,患者无痛苦,轻微不适感短期消失,是诊断乳头溢液病因的首选。该检查手段副损伤及并发症发生率低,且均是可以治愈且不危及生命的,熟练掌握后并发症的发生率会明显降低。血性乳头溢液在肿瘤性乳管内疾病中发生率高,可以发现早期乳腺癌。
目的:探討纖維乳管鏡在自髮性乳頭溢液病因診斷中的效果。方法迴顧性分析行乳管鏡檢查的828例自髮性乳頭溢液患者的臨床資料併結閤最新的文獻資料。結果在乳頭溢液疾病檢查中,乳管鏡的敏感性和特異性分彆為96.4%(798/828)和97.1%(435/448);乳頭溢液中血性溢液髮生率最高58.2%(482/828),引起乳頭溢液疾病中乳管乳頭狀瘤髮病率最高55.1%(456/828),乳腺癌髮病率是7.0%(58/828),其中86.2%(50/58)的是原位癌;乳管內腫瘤疾病以血性的乳頭溢液為主,髮生率是67.8%(472/696);乳管內非腫瘤性疾病中以漿液性、乳汁性、水性的乳頭溢液為主,髮生率90.2%(92/102)(P=0.001)。FDS的副損傷及併髮癥髮生率7.9%,無嚴重併髮癥及死亡病例。結論纖維乳管鏡在乳頭溢液疾病的診斷中敏感性、特異性均較高,而且簡便易行,患者無痛苦,輕微不適感短期消失,是診斷乳頭溢液病因的首選。該檢查手段副損傷及併髮癥髮生率低,且均是可以治愈且不危及生命的,熟練掌握後併髮癥的髮生率會明顯降低。血性乳頭溢液在腫瘤性乳管內疾病中髮生率高,可以髮現早期乳腺癌。
목적:탐토섬유유관경재자발성유두일액병인진단중적효과。방법회고성분석행유관경검사적828례자발성유두일액환자적림상자료병결합최신적문헌자료。결과재유두일액질병검사중,유관경적민감성화특이성분별위96.4%(798/828)화97.1%(435/448);유두일액중혈성일액발생솔최고58.2%(482/828),인기유두일액질병중유관유두상류발병솔최고55.1%(456/828),유선암발병솔시7.0%(58/828),기중86.2%(50/58)적시원위암;유관내종류질병이혈성적유두일액위주,발생솔시67.8%(472/696);유관내비종류성질병중이장액성、유즙성、수성적유두일액위주,발생솔90.2%(92/102)(P=0.001)。FDS적부손상급병발증발생솔7.9%,무엄중병발증급사망병례。결론섬유유관경재유두일액질병적진단중민감성、특이성균교고,이차간편역행,환자무통고,경미불괄감단기소실,시진단유두일액병인적수선。해검사수단부손상급병발증발생솔저,차균시가이치유차불위급생명적,숙련장악후병발증적발생솔회명현강저。혈성유두일액재종류성유관내질병중발생솔고,가이발현조기유선암。
Objective To evaluate the status of mammary fiberoptic ductoscopy in etiologic diagnosis for spontaneous nipple discharge.Methods Clinical data of 828 nipple discharge cases who underwent mammary ductoscopy were collected and combined review of the latest literature.Results Sensitivity and specificity of mammaryfiberoptic ductoscopy are 96.4%(798/828), 97.1%(435/448)respectively in etiologic diagnosis of nipple discharge; bloody nipple discharge was the most common sign with rate of 58.2%(482/828).Intraductal papilloma is the most common disease in nipple discharge with the rate of 55.1%(456/828). Breast cancer is 7.0%(58/828) and 86.2%(50/58)is carcinoma in situ within breast cancer. Bloody nipple discharge is strongly related to intraductal neoplasm disease with rate of 67.8%(472/696); Other kinds of nipple discharge are related to intraductal non-neoplasm disease with the rate of 90.2%(92/102)(P=0.001).The rate of side injury and complication is 7.9%, no severe complication and dead case occurred.Conclusion Mammaryfiberoptic ductoscopy have great advantages in etiologic diagnosis of nipple discharge because of its superior sensitivity and specificity.It has low rate of side injury and complication and all of them are reversible. Quantity of nipple discharge is concerned with kinds of mammary duct disease.It is also helpful in detection early stage breast cancer such as carcinoma in situ.