北京生物医学工程
北京生物醫學工程
북경생물의학공정
Beijing Biomedical Engineering
2015年
5期
505-508
,共4页
张丽华%谷智明%封淑文%王岩
張麗華%穀智明%封淑文%王巖
장려화%곡지명%봉숙문%왕암
冠心病%室壁运动%纵向收缩期峰值应变%斑点追踪技术%工作特征曲线
冠心病%室壁運動%縱嚮收縮期峰值應變%斑點追蹤技術%工作特徵麯線
관심병%실벽운동%종향수축기봉치응변%반점추종기술%공작특정곡선
coronary heart disease%ventricular wall motion%globe longitudinal systolic peak strain%speckle tracking imaging%receiver operating characteristic curve
目的：应用二维斑点追踪成像（ speckle tracking imaging， STI）技术对常规方法显示室壁运动正常的冠心病患者进行定量分析，探讨STI技术用于诊断冠心病的临床应用价值。方法采集经冠状动脉造影证实的50例冠心病和40例对照组患者的心尖长轴、四腔和两腔观的二维灰阶动态图像，测量比较两组各节段纵向收缩期峰值应变（ global longitudinal systolic peak strain， GLPS）及整体纵向平均应变（ GLPS?Avg），应用受试者工作特征曲线（ receiver operating characteristic curve， ROC曲线）评价GLPS?Avg对筛选冠心病的敏感性和特异性。结果冠心病组各节段心肌的GLPS均明显低于对照组，差异性具统计学意义（P＜0?05）。 GLPS?Avg 冠心病组（－15?79％±3?35％）绝对值低于正常组（－19?02％±2?78％）的绝对值，有统计学差异（P＜0?05）。 ROC曲线显示以GLPS?Avg－17?7％作为筛选冠心病的截断值，其诊断敏感性为77?5％，特异性为60?0％，AUC＝0?777。结论 STI作为早期诊断冠心病的指标是可行的。
目的：應用二維斑點追蹤成像（ speckle tracking imaging， STI）技術對常規方法顯示室壁運動正常的冠心病患者進行定量分析，探討STI技術用于診斷冠心病的臨床應用價值。方法採集經冠狀動脈造影證實的50例冠心病和40例對照組患者的心尖長軸、四腔和兩腔觀的二維灰階動態圖像，測量比較兩組各節段縱嚮收縮期峰值應變（ global longitudinal systolic peak strain， GLPS）及整體縱嚮平均應變（ GLPS?Avg），應用受試者工作特徵麯線（ receiver operating characteristic curve， ROC麯線）評價GLPS?Avg對篩選冠心病的敏感性和特異性。結果冠心病組各節段心肌的GLPS均明顯低于對照組，差異性具統計學意義（P＜0?05）。 GLPS?Avg 冠心病組（－15?79％±3?35％）絕對值低于正常組（－19?02％±2?78％）的絕對值，有統計學差異（P＜0?05）。 ROC麯線顯示以GLPS?Avg－17?7％作為篩選冠心病的截斷值，其診斷敏感性為77?5％，特異性為60?0％，AUC＝0?777。結論 STI作為早期診斷冠心病的指標是可行的。
목적：응용이유반점추종성상（ speckle tracking imaging， STI）기술대상규방법현시실벽운동정상적관심병환자진행정량분석，탐토STI기술용우진단관심병적림상응용개치。방법채집경관상동맥조영증실적50례관심병화40례대조조환자적심첨장축、사강화량강관적이유회계동태도상，측량비교량조각절단종향수축기봉치응변（ global longitudinal systolic peak strain， GLPS）급정체종향평균응변（ GLPS?Avg），응용수시자공작특정곡선（ receiver operating characteristic curve， ROC곡선）평개GLPS?Avg대사선관심병적민감성화특이성。결과관심병조각절단심기적GLPS균명현저우대조조，차이성구통계학의의（P＜0?05）。 GLPS?Avg 관심병조（－15?79％±3?35％）절대치저우정상조（－19?02％±2?78％）적절대치，유통계학차이（P＜0?05）。 ROC곡선현시이GLPS?Avg－17?7％작위사선관심병적절단치，기진단민감성위77?5％，특이성위60?0％，AUC＝0?777。결론 STI작위조기진단관심병적지표시가행적。
Objective To investigate the clinical value of speckle tracking imaging ( STI ) in the diagnosis of coronary heart disease ( CHD ) with normal ventricular wall motion? Methods According to the results of coronary angiography, 50 patients with CHD and 40 age?matched subjects were enrolled? The two?dimensional loop?cines were obtained in apical 4-chamber view, apical 2-chamber view and long axis view of left ventricle? Globe longitudinal systolic peak strain ( GLPS ) and average globe longitudinal systolic peak strain ( GLPS?Avg) were measured and calculated? GLPS?Avg were applied to evaluate the diagnostic efficiency for CHD by receiver operating characteristic curve? Results The absolute value of GLPS_Avg in CHD group (-15?79%± 3?35%) was significantly decreased compared with that of the normal group (-19?02%± 2?78%)?The cutoff value of GLPS?Avg to diagnose CHD was-17?7%, with the sensitivity 77?5% and specificity 60?0%.Conclusions GLPS?Avg with STI technique was helpful to diagnose CHD.
