四川医学
四川醫學
사천의학
Sichuan Medical Journal
2015年
10期
1420-1422
,共3页
肺结核%结核性脑膜炎%初治%复治%疗效
肺結覈%結覈性腦膜炎%初治%複治%療效
폐결핵%결핵성뇌막염%초치%복치%료효
pulmonary tuberculosis%tubercular meningitis%valid initial treatment%valid re-treatment therapeutic%effect
目的 总结初治肺结核并结核性脑膜炎的疗效,探讨抗结核方案对结核性脑膜炎转归的影响. 方法 回顾性分析我院156 例初治肺结核并结核性脑膜炎抗结核治疗及疗效. 结果 初治抗结核方案( HREZS )有效52 例(33. 34%),复治抗结核方案(Pas Pto PZA Lfx Am)有效83例(79. 81%),治疗无效21例(13. 47%). 结论 复治方案抗结核治疗有效率明显高于初治方案,晚期结核性脑膜炎治疗效果相对较差. 原发耐药率低、易透过血脑屏障的结核药组成合理的抗结核方案治疗,治愈率明显提高,可一定程度改善预后.
目的 總結初治肺結覈併結覈性腦膜炎的療效,探討抗結覈方案對結覈性腦膜炎轉歸的影響. 方法 迴顧性分析我院156 例初治肺結覈併結覈性腦膜炎抗結覈治療及療效. 結果 初治抗結覈方案( HREZS )有效52 例(33. 34%),複治抗結覈方案(Pas Pto PZA Lfx Am)有效83例(79. 81%),治療無效21例(13. 47%). 結論 複治方案抗結覈治療有效率明顯高于初治方案,晚期結覈性腦膜炎治療效果相對較差. 原髮耐藥率低、易透過血腦屏障的結覈藥組成閤理的抗結覈方案治療,治愈率明顯提高,可一定程度改善預後.
목적 총결초치폐결핵병결핵성뇌막염적료효,탐토항결핵방안대결핵성뇌막염전귀적영향. 방법 회고성분석아원156 례초치폐결핵병결핵성뇌막염항결핵치료급료효. 결과 초치항결핵방안( HREZS )유효52 례(33. 34%),복치항결핵방안(Pas Pto PZA Lfx Am)유효83례(79. 81%),치료무효21례(13. 47%). 결론 복치방안항결핵치료유효솔명현고우초치방안,만기결핵성뇌막염치료효과상대교차. 원발내약솔저、역투과혈뇌병장적결핵약조성합리적항결핵방안치료,치유솔명현제고,가일정정도개선예후.
Objective To conclude therapeutic effect of the Initial treatment of pulmonary tuberculosis combined with tu-bercular meningitis, and explored how antituberculous plans influence the outcome of tuberculosis meningitis. Methods Retro-spective analysis of the treatment and therapeutic effect on 156 initial treatment of pulmonary tuberculosis combined with tubercular meningitis. Results Valid initial treatment:52(33. 34%), valid re-treatment:83(79. 81%), invalid treatment 21(13. 47%). Conclusion For valid rate of treating tuberculosis meningitis, re-treatment showed a better effect than initial treatment. The valid rate of treating advanced stage of tuberculosis meningitis was not satisfactory. Drug resistance rate performed low at primary stage. Some drugs easily penetrated through blood brain barrier( BBB) and were composed a reasonable antituberculous plan, which sig-nificantly enhanced the cure rate. To some degree, this plan can improve prognosis.
