CAJ | 학술논문

在日常的骨密度检查中，很少发现骨密度升高的情况且常常被临床医生忽视。并非所有的骨密度升高均有利于骨骼的健康，部分骨密度升高可能导致骨骼脆性增加从而增加骨折的风险，同时可表现出其原发疾病的致命性临床症状。许多因素均可导致骨密度的升高，如局部组织的钙化、肿瘤的骨转移、氟骨病及罕见的遗传性疾病等，给临床医生诊断及治疗带来巨大挑战。虽然目前缺乏对骨密度升高的大规模研究，大多数研究仍停留在个案报道，但近年来对骨密度升高的诊断标准、流行病学特征、临床表现、原因及管理措施方面仍有较大的进展。
재일상적골밀도검사중，흔소발현골밀도승고적정황차상상피림상의생홀시。병비소유적골밀도승고균유리우골격적건강，부분골밀도승고가능도치골격취성증가종이증가골절적풍험，동시가표현출기원발질병적치명성림상증상。허다인소균가도치골밀도적승고，여국부조직적개화、종류적골전이、불골병급한견적유전성질병등，급림상의생진단급치료대래거대도전。수연목전결핍대골밀도승고적대규모연구，대다수연구잉정류재개안보도，단근년래대골밀도승고적진단표준、류행병학특정、림상표현、원인급관리조시방면잉유교대적진전。
Increase of bone mineral density is rarely found and it has most commonly been ignored by clinicians during daily DXA scan.Not all the high bone mineral density is beneficial to bone health.Part of the increase of bone mineral density may lead to increased bone fragility and risk of the fracture.It also exhibits lethal clinical symptoms of other primary diseases.Many factors lead to the increased of bone mineral density, such as local tissue calcification, tumor bone metastasis, bone fluoride, and rare genetic diseases, which bring great challenges to clinicians in the diagnosis and treatment of high bone mineral density.There are not enough large-scale studies on high bone mineral density and most of the studies are case reports at present.However, the diagnosis criteria, epidemiological characteristics, clinical manifestations, causes and management measures of increased bone mineral density still have a great progress in recent years.