药学与临床研究
藥學與臨床研究
약학여림상연구
Pharmaceutical and Clinical Research
2015年
5期
490-493
,共4页
急性心肌梗死%抗栓治疗%消化道损伤%质子泵抑制剂
急性心肌梗死%抗栓治療%消化道損傷%質子泵抑製劑
급성심기경사%항전치료%소화도손상%질자빙억제제
Acute myocardial infarction%Drug use evaluation (DUE)%Proton pump inhibitors (PPIs)
目的:分析急性心肌梗死患者质子泵抑制剂(PPI)的使用情况,建立药物利用评价标准。方法:收集我院心血管内科2013年1月~2014年6月出院的急性心肌梗死患者的病例资料,对PPI的使用情况进行分析。结果:共纳入291例患者,PPI使用率91.4%,平均用药(10.3±4.2) d,给药方式口服、静脉继以口服为主,静脉途径多用泮托拉唑,平均剂量(54.0±19.2) mg·d-1,口服途径多用雷贝拉唑,平均剂量(18.1±4.2) mg·d-1。结论:我院心梗患者PPI使用率高、疗程较长,选药品种及用法用量基本合理;需加强对给药剂量和疗程的控制。
目的:分析急性心肌梗死患者質子泵抑製劑(PPI)的使用情況,建立藥物利用評價標準。方法:收集我院心血管內科2013年1月~2014年6月齣院的急性心肌梗死患者的病例資料,對PPI的使用情況進行分析。結果:共納入291例患者,PPI使用率91.4%,平均用藥(10.3±4.2) d,給藥方式口服、靜脈繼以口服為主,靜脈途徑多用泮託拉唑,平均劑量(54.0±19.2) mg·d-1,口服途徑多用雷貝拉唑,平均劑量(18.1±4.2) mg·d-1。結論:我院心梗患者PPI使用率高、療程較長,選藥品種及用法用量基本閤理;需加彊對給藥劑量和療程的控製。
목적:분석급성심기경사환자질자빙억제제(PPI)적사용정황,건립약물이용평개표준。방법:수집아원심혈관내과2013년1월~2014년6월출원적급성심기경사환자적병례자료,대PPI적사용정황진행분석。결과:공납입291례환자,PPI사용솔91.4%,평균용약(10.3±4.2) d,급약방식구복、정맥계이구복위주,정맥도경다용반탁랍서,평균제량(54.0±19.2) mg·d-1,구복도경다용뢰패랍서,평균제량(18.1±4.2) mg·d-1。결론:아원심경환자PPI사용솔고、료정교장,선약품충급용법용량기본합리;수가강대급약제량화료정적공제。
Objective: To investigate the usage of proton pump inhibitors (PPIs) in patients with acute my-ocardial infarction, and to establish DUE criteria of PPIs. Methods: The usage of PPIs was analyzed with the data taken from the hospitalized cases with acute myocardial infarction from Jan. 2013 to Jun. 2014. Results: A total of 291 cases were enrolled. PPIs were used in 91.4% patients, and the average use dura-tion of each patients was (10.3 ±4.2) d. The main routes of administration were oral or intravenous-to-oral. Pantoprazole was the most used PPI through intravenous administration, with average dosage of (54.0±19.2) mg·d-1. Rabeprazole was the most used PPI through oral administration, with average dosage of (18.1±4.2) mg·d-1. Conclusion: PPIs were frequently used in long course of treatment. The choice of PPIs, dosage and administration were rational. Further efforts should be made on the dosage of administration and course of treatment.