中国骨质疏松杂志
中國骨質疏鬆雜誌
중국골질소송잡지
Chinese Journal of Osteoporosis
2015年
10期
1221-1225,1229
,共6页
老年%维生素D缺乏%甲状旁腺素%骨密度
老年%維生素D缺乏%甲狀徬腺素%骨密度
노년%유생소D결핍%갑상방선소%골밀도
The elderly%Vitamin D deficiency%Parathyroid hormone%BMD
目的：通过调查呼和浩特市老干部的维生素D营养状况，和对骨密度及骨折风险的影响，为进一步防治骨质疏松及维生素D缺乏引起的各种疾病提供理论基础。方法随机选取2012年11月～2013年9月在内蒙古自治区人民医院干部保健所就诊、体检的年龄60岁以上的干部268例，最终入选235例。对入选对象进行一般情况调查，并抽血测定25（OH）D、PTH等生化指标，同时进行骨密度测定。对所有数据进行整理，用IBM SPSS统计软件包进行统计分析。结果235名研究对象中，血25（OH）D浓度为13?51±8?59ng／mL。 PTH浓度为45?99±20?02pg／mL。骨密度：股骨颈为0?690±0?144 g／cm2，总髋部为0?818±0?158 g／cm2，腰椎1－4为0?978±0?207 g／cm2。10年主要骨质疏松骨折概率为3?29±2?66％，10年髋部骨折概率1?36±1?59％。总25（OH）D水平与10年主要骨质疏松骨折概率、10年髋部骨折概率均负相关。结论呼和浩特市老年干部维生素D缺乏和不足十分严重，骨质疏松患病率较高，应引起足够重视。
目的：通過調查呼和浩特市老榦部的維生素D營養狀況，和對骨密度及骨摺風險的影響，為進一步防治骨質疏鬆及維生素D缺乏引起的各種疾病提供理論基礎。方法隨機選取2012年11月～2013年9月在內矇古自治區人民醫院榦部保健所就診、體檢的年齡60歲以上的榦部268例，最終入選235例。對入選對象進行一般情況調查，併抽血測定25（OH）D、PTH等生化指標，同時進行骨密度測定。對所有數據進行整理，用IBM SPSS統計軟件包進行統計分析。結果235名研究對象中，血25（OH）D濃度為13?51±8?59ng／mL。 PTH濃度為45?99±20?02pg／mL。骨密度：股骨頸為0?690±0?144 g／cm2，總髖部為0?818±0?158 g／cm2，腰椎1－4為0?978±0?207 g／cm2。10年主要骨質疏鬆骨摺概率為3?29±2?66％，10年髖部骨摺概率1?36±1?59％。總25（OH）D水平與10年主要骨質疏鬆骨摺概率、10年髖部骨摺概率均負相關。結論呼和浩特市老年榦部維生素D缺乏和不足十分嚴重，骨質疏鬆患病率較高，應引起足夠重視。
목적：통과조사호화호특시로간부적유생소D영양상황，화대골밀도급골절풍험적영향，위진일보방치골질소송급유생소D결핍인기적각충질병제공이론기출。방법수궤선취2012년11월～2013년9월재내몽고자치구인민의원간부보건소취진、체검적년령60세이상적간부268례，최종입선235례。대입선대상진행일반정황조사，병추혈측정25（OH）D、PTH등생화지표，동시진행골밀도측정。대소유수거진행정리，용IBM SPSS통계연건포진행통계분석。결과235명연구대상중，혈25（OH）D농도위13?51±8?59ng／mL。 PTH농도위45?99±20?02pg／mL。골밀도：고골경위0?690±0?144 g／cm2，총관부위0?818±0?158 g／cm2，요추1－4위0?978±0?207 g／cm2。10년주요골질소송골절개솔위3?29±2?66％，10년관부골절개솔1?36±1?59％。총25（OH）D수평여10년주요골질소송골절개솔、10년관부골절개솔균부상관。결론호화호특시노년간부유생소D결핍화불족십분엄중，골질소송환병솔교고，응인기족구중시。
Objectives To study the vitamin D status and its effect on BMD and fracture risk in the elderly cadres in Hohhot, in order to provide theoretical reference for further prevention and treatment of various diseases caused by osteoporosis and vitamin D deficiency. Methods A total of 268 over 60 years old cadres who received treatment or physical examination in Cadre Health Centre of People’ s Hospital of Inner Mongolia Autonomous from November 2012 to September 2013 were randomly selected, and 235 of them were finally selected in this study. Questionnaire survey was performed in the selected subjects to understand their general condition. 25(OH)D, PTH, and biochemical markers were examined. Bone mineral density (BMD) was measured. All of the data obtained were statistically analyzed with IBM SPSS statistical package. Results In the 235 subjects, serum 25(OH)D concentration was 13?51 ± 8?59 ng/ml, PTH concentration was 45?99 ± 20?02 pg/ml, and BMD was 0?690 ± 0?144 g/cm2 in the femoral neck, 0?818 ± 0?158 g/cm2 in the total hip, and 0?978 ± 0?207 g/cm2 in the lumbar vertebrae 1?4. The 10?year major osteoporotic fracture probability was 3?29 ±2?66%. The 10?year hip fracture probability was 1?36 ±1?59%. The total 25(OH)D level was negatively correlated with 10?year major osteoporotic fracture probability and 10?year hip fracture probability. Conclusion Vitamin D deficiency and insufficiency in elderly cadres in Hohhot are very serious, and the prevalence of osteoporosis is high, which should be paid close attention.
