CAJ | 학술논문

目的：分析妊娠合并乙型肝炎病毒（HBV）感染对母婴的影响。方法比较分析2013年10月至2014年10月75例妊娠合并HBV感染孕产妇（A组）、75例无症状HBV携带孕产妇（B组）和75例健康孕产妇（C组）的临床资料，探讨妊娠合并HBV感染对母婴的影响。结果 A组产妇孕早期妊娠期高血压综合征发生率、死胎引产率，产时胎儿窘迫、胎膜早破、产后出血发生率及新生儿死胎、早产、低体质量、新生儿窒息发生率均显著高于C组，差异均有统计学意义（P<0.05）；三组产妇孕早期阴道流血发生率、妊娠剧吐发生率、自然分娩率、剖宫产率、阴道助产率比较，差异均无统计学意义（P>0.05）；B组与C组产妇产时胎儿窘迫、胎膜早破、产后出血发生率及新生儿死胎、早产、低体质量、新生儿窒息发生率比较，差异均无统计学意义（P>0.05）。结论妊娠合并HBV感染可增加妊娠期高血压综合征、胎儿窘迫、胎膜早破、产后出血发生率及新生儿死胎、早产、低体质量、新生儿窒息发生率，对母婴影响较大，应注意产前及妊娠期检查。
목적：분석임신합병을형간염병독（HBV）감염대모영적영향。방법비교분석2013년10월지2014년10월75례임신합병HBV감염잉산부（A조）、75례무증상HBV휴대잉산부（B조）화75례건강잉산부（C조）적림상자료，탐토임신합병HBV감염대모영적영향。결과 A조산부잉조기임신기고혈압종합정발생솔、사태인산솔，산시태인군박、태막조파、산후출혈발생솔급신생인사태、조산、저체질량、신생인질식발생솔균현저고우C조，차이균유통계학의의（P<0.05）；삼조산부잉조기음도류혈발생솔、임신극토발생솔、자연분면솔、부궁산솔、음도조산솔비교，차이균무통계학의의（P>0.05）；B조여C조산부산시태인군박、태막조파、산후출혈발생솔급신생인사태、조산、저체질량、신생인질식발생솔비교，차이균무통계학의의（P>0.05）。결론임신합병HBV감염가증가임신기고혈압종합정、태인군박、태막조파、산후출혈발생솔급신생인사태、조산、저체질량、신생인질식발생솔，대모영영향교대，응주의산전급임신기검사。
Objective To analyze the effect of pregnancy complicating hepatitis B virus (HBV) infection on maternaty and infant. Methods The clinical data in 75 parturients of pregnancy complicating HBV infection (group A),75 parturients of non-symptom carrying HBV(B group) and 75 healthy parturients(group C) from October 2013 to October 2014 were comparatively analyzed for investigating the influence of pregnancy complicating HBV infection on maternaty and infant. Results The occur-rence rates of early pregnancy induced hypertension syndrome(PIHS),stillbirth induced labor rate,intrapartum fetal distress, premature rupture of fetal membranes, postpartum bleeding,neonatal stillbirth,premature,low body mass and neonatal asphyxia in the group A was significantly higher than that in the group C,the difference were statistically significant (P<0.05);the early vaginal bleeding during early pregnant period,occurrence rate of hyperemesis gravidarum,spontaneous labor rate,cesarean section rate and vaginal instrumental delivery rate had no statistical differences among 3 groups (P>0.05);the occurrence rates of fetal dis-tress at labor,premature rupture of fetal membrane,postpartum bleeding,neonatal stillbirth,premature,low body mass and neona tal asphyxia had no statistical differences between the group B and C (P>0.05). Conclusion Pregnancy complicating HBV infection may increase the incidence rates of PIHS,fetal distress,premature rupture of fetal membranes and postpartum hemorrhage and the incidence rates of neonatal stillbirth,premature,low body mass and neonatal asphyxia,has a greater impact on maternity and in-fant. Therefore the prenatal examination and pregnant period examination should be paid attention to.