CAJ | 학술논문

脂代谢紊乱和骨质疏松症均是代谢性疾病。近年来发现脂代谢紊乱易合并骨质疏松，研究二者的相关性，对预防与治疗骨质疏松有一定临床指导意义。骨代谢包括骨生成和骨吸收，血脂则包含总胆固醇、甘油三酯、低密度脂蛋白胆固醇和高密度脂蛋白胆固醇等几个方面，研究脂代谢与骨代谢之间的关系，涉及到多种血脂与成骨细胞及破骨细胞的关系，关于二者相互影响的分子机理目前有了一定的研究成果，本文就二者相关性的可能机制作一综述。
지대사문란화골질소송증균시대사성질병。근년래발현지대사문란역합병골질소송，연구이자적상관성，대예방여치료골질소송유일정림상지도의의。골대사포괄골생성화골흡수，혈지칙포함총담고순、감유삼지、저밀도지단백담고순화고밀도지단백담고순등궤개방면，연구지대사여골대사지간적관계，섭급도다충혈지여성골세포급파골세포적관계，관우이자상호영향적분자궤리목전유료일정적연구성과，본문취이자상관성적가능궤제작일종술。
Osteoporosis and dyslipidemia are metabolic diseases. It has been found that the probability of osteoporosis concurrent dyslipidemia increases in recent years. The study of the relationship between osteoporosis and dyslipidemia has certain guiding meaning in the prevention and treatment of osteoporosis. Bone metabolism includes bone formation and bone resorption. Serum lipid contains total cholesterol, triglyceride, low density lipoprotein cholesterol, and high density lipoprotein cholesterol etc. The study of the relationship between serum lipid disorders and osteoporosis is the study of the relationship between the different kinds of serum lipid and osteoblasts and osteoclasts. At present, there is progress in the molecular mechanism of the interaction between both factors. This paper reviews the possible mechanism of the relationship between lipid metabolism and bone metabolism.