CAJ | 학술논문

目的：了解北京社区精神分裂症患者发生2型糖尿病的比例及其人口学特点。方法以北京市4个区县540名18～65岁慢性精神分裂症患者作为调查对象。使用一般人口学特征、疾病特征、用药情况、糖尿病病史登记表等进行访谈，检测身高、体质量及空腹血糖。结果精神分裂症患者糖尿病的发生率为15．7％，有随着年龄的增长而增加的趋势（P＜0．05）；单因素分析显示精神分裂症糖尿病患者与非糖尿病患者在发病次数、发病年龄、总病程方面比较差异有统计学意义（P＜0．05）。 Logistic回归分析显示控制其他影响因素的情况下，糖尿病的发生与急性起病、病程长、发病年龄晚有关（ P＜0．05）。结论慢性精神分裂症患者中糖尿病的发生率高于正常人群，与发病形式、发病年龄和病程有关。
목적：료해북경사구정신분렬증환자발생2형당뇨병적비례급기인구학특점。방법이북경시4개구현540명18～65세만성정신분렬증환자작위조사대상。사용일반인구학특정、질병특정、용약정황、당뇨병병사등기표등진행방담，검측신고、체질량급공복혈당。결과정신분렬증환자당뇨병적발생솔위15．7％，유수착년령적증장이증가적추세（P＜0．05）；단인소분석현시정신분렬증당뇨병환자여비당뇨병환자재발병차수、발병년령、총병정방면비교차이유통계학의의（P＜0．05）。 Logistic회귀분석현시공제기타영향인소적정황하，당뇨병적발생여급성기병、병정장、발병년령만유관（ P＜0．05）。결론만성정신분렬증환자중당뇨병적발생솔고우정상인군，여발병형식、발병년령화병정유관。
Objective To explore the prevalence rate and demographic characteristics of type II diabetes mellitus in patients with schizophrenia in Beijing community.Methods A total of 540 patients with chronic schizophrenia from 18 to 65 years old in four districts and counties of Beijing were selected and investigated with basic socio-demographic, disease attribute,medication, history of diabetes, height, weight and fasting blood glucose.Results The prevalence rate of diabetes mellitus in patients with schizophrenia was 15.7% which was positively related with the age of patients ( P <0.05).Univariate analysis showed significant differences for recurrence times, age of onset and course of disease between the schizophsenia patients with diabetes mellitus and the schizophrenia patients without diabetes mellitus (P<0.05).Logistic regression analysis showed the onset of diabetes mellitus in the patients was related to acute onset, long course of disease and late age of onset (P<0.05).Conclusion It’s serious for the prevalence rate of diabetes mellitus in patients with schizophrenia which is related to the form and age of onset as well as course of disease.