中国民族民间医药
中國民族民間醫藥
중국민족민간의약
Chinese Journal of Ethnomedicine and Ethnopharmacy
2015年
20期
53-54
,共2页
冠心病%瑞舒伐他汀%阿托伐他汀%降脂药物
冠心病%瑞舒伐他汀%阿託伐他汀%降脂藥物
관심병%서서벌타정%아탁벌타정%강지약물
Coronary heart disease%Rosuvastatin%Atorvastatin%Lipid lowering drugs
目的：观察冠心病患者应用瑞舒伐他汀与阿托伐他汀的治疗效果。方法：选取冠心病患者240例，将其分为实验组和对照组各120例。实验组患者口服瑞舒伐他汀片；对照组患者口服阿托伐他汀片。治疗前后测量患者的血清总胆固醇（Total cholesterol， TC）、甘油三酯（Triglyceride ，TG）、低密度脂蛋白胆固醇（Low density lipoprotein cholesterol，LDL －C）、高密度脂蛋白胆固醇（High den-sity lipoprotein cholesterol，HDL －C）等血脂指标的水平，记录在治疗期间不良事件以及肝肾功能情况。结果：实验组和对照组患者在治疗后体内 TG、TC、LDL －C、HDL －C 等指标优于治疗前，实验组患者的 TG、TC、LDL －C、HDL －C 等血脂水平均优于对照组。实验组的总有效率94．2％，显著高于对照组的70．8％（P ＜0．05）。结论：两种药物都能有效地改善冠心病患者的血脂水平，降低血脂 TG、TC、LDL－C 水平，有利于动脉粥样硬化的延迟或逆转，但瑞舒伐他汀的临床效果更佳。
目的：觀察冠心病患者應用瑞舒伐他汀與阿託伐他汀的治療效果。方法：選取冠心病患者240例，將其分為實驗組和對照組各120例。實驗組患者口服瑞舒伐他汀片；對照組患者口服阿託伐他汀片。治療前後測量患者的血清總膽固醇（Total cholesterol， TC）、甘油三酯（Triglyceride ，TG）、低密度脂蛋白膽固醇（Low density lipoprotein cholesterol，LDL －C）、高密度脂蛋白膽固醇（High den-sity lipoprotein cholesterol，HDL －C）等血脂指標的水平，記錄在治療期間不良事件以及肝腎功能情況。結果：實驗組和對照組患者在治療後體內 TG、TC、LDL －C、HDL －C 等指標優于治療前，實驗組患者的 TG、TC、LDL －C、HDL －C 等血脂水平均優于對照組。實驗組的總有效率94．2％，顯著高于對照組的70．8％（P ＜0．05）。結論：兩種藥物都能有效地改善冠心病患者的血脂水平，降低血脂 TG、TC、LDL－C 水平，有利于動脈粥樣硬化的延遲或逆轉，但瑞舒伐他汀的臨床效果更佳。
목적：관찰관심병환자응용서서벌타정여아탁벌타정적치료효과。방법：선취관심병환자240례，장기분위실험조화대조조각120례。실험조환자구복서서벌타정편；대조조환자구복아탁벌타정편。치료전후측량환자적혈청총담고순（Total cholesterol， TC）、감유삼지（Triglyceride ，TG）、저밀도지단백담고순（Low density lipoprotein cholesterol，LDL －C）、고밀도지단백담고순（High den-sity lipoprotein cholesterol，HDL －C）등혈지지표적수평，기록재치료기간불량사건이급간신공능정황。결과：실험조화대조조환자재치료후체내 TG、TC、LDL －C、HDL －C 등지표우우치료전，실험조환자적 TG、TC、LDL －C、HDL －C 등혈지수평균우우대조조。실험조적총유효솔94．2％，현저고우대조조적70．8％（P ＜0．05）。결론：량충약물도능유효지개선관심병환자적혈지수평，강저혈지 TG、TC、LDL－C 수평，유리우동맥죽양경화적연지혹역전，단서서벌타정적림상효과경가。
Objective To study the efficacy of coronary heart disease patients with rosuvastatin and atorvastatin therapy.Methods Select 240 cases of coronary heart disease patients,and they were divided into experimental group and control group.The experimen-tal group in patients with coronary heart disease use rosuvastatin and the control group use simvastatin.Measurement of serum total cho-lesterol in vivo respectively before and after treatment Total cholesterol (TC),three glycerol (TG)phthalate,low density lipoprotein cholesterol (LDL -C),high density lipoprotein cholesterol (HDL -C)and blood lipid levels,and record adverse events during treat-ment,liver and kidney function.Results Two groups of patients after treatment,the serum levels of total cholesterol (TC),after three glycerol phthalate (TG),low density lipoprotein cholesterol (LDL -C)and other indicators were lower than before treatment. After treatment of patients in the experimental group compared with the TG,TC,LDL -C,HDL -C and blood lipid levels in the control group were better.The experimental group total effective rate was 94.2% ,higher than the control group of patients with total effective rate was 70.8% (P <0.05).Conclusion The two kinds of drug can effectively improve the blood lipid levels in patients with coronary heart disease,reduce blood TG,TC,LDL -C level,which is beneficial to delay or reverse the process of atherosclero-sis,but the effect of rosuvastatin have a better clinical effect.
