广西医学
廣西醫學
엄서의학
Guangxi Medical Journal
2015年
8期
1096-1099
,共4页
2型糖尿病%肥胖%减重%综合内科治疗%穴位埋线%饮食%运动控制
2型糖尿病%肥胖%減重%綜閤內科治療%穴位埋線%飲食%運動控製
2형당뇨병%비반%감중%종합내과치료%혈위매선%음식%운동공제
Type 2 diabetes%Obesity%Weight loss%Internal medicine%Synthetical internal medicine treatment%Catgut embedding therapy%Diet%Exercise control
目的 观察内科综合减重方案治疗肥胖型2型糖尿病的临床效果. 方法 选取肥胖型2型糖尿病患者60例,采用随机数字表法分为对照组和观察组,每组30例,两组均给予二甲双胍口服,对照组患者根据自己意愿进行饮食、运动治疗;观察组予内科综合减重方案,包括穴位埋线、饮食、运动控制. 观察治疗前、治疗后4周、8周、12周时糖化血红蛋白(HbA1c)、空腹血糖(FBG)、餐后2h血糖(P2hBG)、体重、体重指数(BMI)、腰围、腰臀比(WHR)变化及治疗前后空腹胰岛素水平(FINS)、胰岛素敏感指数(IAI)、胰岛素抵抗指数(HOMA-IR)、胆固醇(TC)、甘油三酯(TG)、低密度脂蛋白(LDL)、高密度脂蛋白(HDL)变化. 结果 随着治疗时间的延长,两组FBG、P2hBG、HbA1c、体重、BMI、腰围、WHR逐渐改善(P<0.05),并且治疗后观察组上述指标改善更为明显(P<0.05);治疗后两组FINS、IAI、HOMA-IR、HDL、LDL、TC、TG均改善(P<0.05),但观察组改善更为明显(P<0.05). 结论 内科综合减重方案治疗肥胖型2型糖尿病患者能明显改善患者血糖、血脂以及胰岛功能,是一种安全有效的治疗方案.
目的 觀察內科綜閤減重方案治療肥胖型2型糖尿病的臨床效果. 方法 選取肥胖型2型糖尿病患者60例,採用隨機數字錶法分為對照組和觀察組,每組30例,兩組均給予二甲雙胍口服,對照組患者根據自己意願進行飲食、運動治療;觀察組予內科綜閤減重方案,包括穴位埋線、飲食、運動控製. 觀察治療前、治療後4週、8週、12週時糖化血紅蛋白(HbA1c)、空腹血糖(FBG)、餐後2h血糖(P2hBG)、體重、體重指數(BMI)、腰圍、腰臀比(WHR)變化及治療前後空腹胰島素水平(FINS)、胰島素敏感指數(IAI)、胰島素牴抗指數(HOMA-IR)、膽固醇(TC)、甘油三酯(TG)、低密度脂蛋白(LDL)、高密度脂蛋白(HDL)變化. 結果 隨著治療時間的延長,兩組FBG、P2hBG、HbA1c、體重、BMI、腰圍、WHR逐漸改善(P<0.05),併且治療後觀察組上述指標改善更為明顯(P<0.05);治療後兩組FINS、IAI、HOMA-IR、HDL、LDL、TC、TG均改善(P<0.05),但觀察組改善更為明顯(P<0.05). 結論 內科綜閤減重方案治療肥胖型2型糖尿病患者能明顯改善患者血糖、血脂以及胰島功能,是一種安全有效的治療方案.
목적 관찰내과종합감중방안치료비반형2형당뇨병적림상효과. 방법 선취비반형2형당뇨병환자60례,채용수궤수자표법분위대조조화관찰조,매조30례,량조균급여이갑쌍고구복,대조조환자근거자기의원진행음식、운동치료;관찰조여내과종합감중방안,포괄혈위매선、음식、운동공제. 관찰치료전、치료후4주、8주、12주시당화혈홍단백(HbA1c)、공복혈당(FBG)、찬후2h혈당(P2hBG)、체중、체중지수(BMI)、요위、요둔비(WHR)변화급치료전후공복이도소수평(FINS)、이도소민감지수(IAI)、이도소저항지수(HOMA-IR)、담고순(TC)、감유삼지(TG)、저밀도지단백(LDL)、고밀도지단백(HDL)변화. 결과 수착치료시간적연장,량조FBG、P2hBG、HbA1c、체중、BMI、요위、WHR축점개선(P<0.05),병차치료후관찰조상술지표개선경위명현(P<0.05);치료후량조FINS、IAI、HOMA-IR、HDL、LDL、TC、TG균개선(P<0.05),단관찰조개선경위명현(P<0.05). 결론 내과종합감중방안치료비반형2형당뇨병환자능명현개선환자혈당、혈지이급이도공능,시일충안전유효적치료방안.
Objective To observe the clinical efficacy of synthetical internal medicine treatment for weight loss on obese patients with type 2 diabetes.Methods Sixty obese patients with type 2 diabetes were randomly divided into control group(n=30) and observation group(n=30).Both groups were orally administered metformin.The diet and exercise treatment was performed in the control group according to the patients′willingness.And the synthetical internal medicine treatment for weight loss was performed in the observation group,including acupoint catgut embedding therapy,diet and exercise control.The changes in glycosylated hemoglobin(HbA1c),fasting blood glucose(FBG), postprandial 2-hour blood glucose(P2hBG),body weight,body mass index(BMI),waist circumference and waist to hip ratio(WHR) were observed before treatment,4,8 and 12 weeks after treatment,respectively.And the levels of fasting insulin(FINS),insulin sensitivity index (IAI),insulin resistance index(HOMA-IR),total cholesterol(TC),triglyceride(TG),low density lipoprotein(LDL) and high density lipoprotein(HDL) were also recorded before and after treatment.Results With the advance of therapy time,FBG,P2hBG,HbA1c,body weight,BMI,waist circumference and WHR improved gradually in two groups(P<0.05),and these indices in the observation group improved more obviously(P<0.05).FINS,IAI,HOMA-IR,LDL,HDL,TC and TG improved after treatment in two groups (P<0.05),and the improvement was more remarkable in the observation group (P<0.05).Conclusion For obese patients with type 2 diabetes,the synthetical internal medicine treatment for weight loss can improve their blood glucose,serum lipid and islet function,which is an effective and safe therapy.
