CAJ | 학술논문

目的：比较重症急性胰腺炎治疗中早期肠内营养和肠外营养的疗效。方法56例重症急性胰腺炎患者随机分为两组，对照组予肠外营养治疗，观察组予早期肠内营养治疗，比较两组患者临床症状、炎症、营养及预后指标的差异。结果治疗后观察组血清CRP及APACHEⅡ评分低于对照组，白蛋白高于对照组，差异均有统计学意义（ P ＜0．05）；观察组患者腹痛腹胀缓解时间、血淀粉酶恢复时间及住院时间均明显短于对照组，且观察组胰腺感染发生率明显低于对照组，差异均有统计学意义（ P ＜0．05）。结论重症急性胰腺炎治疗中采用早期肠内营养治疗可降低炎症反应程度，改善营养状态，促进临床症状的缓解，减少感染并发症的发生，对疾病的恢复有利。
목적：비교중증급성이선염치료중조기장내영양화장외영양적료효。방법56례중증급성이선염환자수궤분위량조，대조조여장외영양치료，관찰조여조기장내영양치료，비교량조환자림상증상、염증、영양급예후지표적차이。결과치료후관찰조혈청CRP급APACHEⅡ평분저우대조조，백단백고우대조조，차이균유통계학의의（ P ＜0．05）；관찰조환자복통복창완해시간、혈정분매회복시간급주원시간균명현단우대조조，차관찰조이선감염발생솔명현저우대조조，차이균유통계학의의（ P ＜0．05）。결론중증급성이선염치료중채용조기장내영양치료가강저염증반응정도，개선영양상태，촉진림상증상적완해，감소감염병발증적발생，대질병적회복유리。
Objective To compare the efficacy of enteral nutrition and parenteral nutrition in the treatment of severe acute pan-creatitis .Methods 56 patients with severe acute pancreatitis were randomly divided into control group and observation group.The control group received parenteral nutrition treatment, and the observation group were given early enteral nutrition therapy.The clinical symptoms, inflammation, nutrition and prognostic indicator in two groups were compared.Results After treatment, the serum CRP and APACHEⅡscores in observation group was lower than those in control group, and albumin was also higher than that in control group, the differences were of statistically significant( P <0.05);the abdominal bloating relief time, blood amylase recovery time and hospital stay in observation group were significantly shorter than those in control group, and the incidence of pancreatic infection in ob-servation group was significantly lower than that in control group, the difference were of statistically significant( P <0.05).Conclu-sion The early enteral nutrition therapy in treatment of severe acute pancreatitis can reduce the degree of inflammation, improve nutri-tional status, promote remission of clinical symptoms, reduce the incidence of infectious complications, and is good for the recovery of the disease.