CAJ | 학술논문

目的：本研究旨在阐述不同急性卒中治疗org10172（Trial of org10172 in Acute Stroke Treatment，TOAST）分型脑梗死患者早期康复治疗的效果及其对神经功能恢复的影响。方法入选脑梗死患者共361例。按TOAST分型：大动脉粥样硬化型（LVA），心源性栓塞型（CE），小动脉闭塞性卒中和腔隙性梗死型（LACI），其它原因及不明原因型（SOD＆SUD）。各亚型患者再分为早期康复治疗组及未干预组，记录患者，治疗1月后及随访6月后的美国国立卫生院卒中神经功能缺损评分量表（ National Institutes of Health Stroke Scale，NIHSS），Barthel Index评分及Rankin评分。结果入院时，腔隙性梗死型患者Barthel Index评分明显高于心源性栓塞型患者。发病6个月后，心源性栓塞型和大动脉粥样硬化型患者康复治疗组Barthel Index评分较未干预组高。结论早期康复治疗可用于脑梗死的治疗，特别是TOAST分型中的心源性栓塞型和大动脉粥样硬化型患者，对远期神经功能的恢复起到良好效果。
목적：본연구지재천술불동급성졸중치료org10172（Trial of org10172 in Acute Stroke Treatment，TOAST）분형뇌경사환자조기강복치료적효과급기대신경공능회복적영향。방법입선뇌경사환자공361례。안TOAST분형：대동맥죽양경화형（LVA），심원성전새형（CE），소동맥폐새성졸중화강극성경사형（LACI），기타원인급불명원인형（SOD＆SUD）。각아형환자재분위조기강복치료조급미간예조，기록환자，치료1월후급수방6월후적미국국립위생원졸중신경공능결손평분량표（ National Institutes of Health Stroke Scale，NIHSS），Barthel Index평분급Rankin평분。결과입원시，강극성경사형환자Barthel Index평분명현고우심원성전새형환자。발병6개월후，심원성전새형화대동맥죽양경화형환자강복치료조Barthel Index평분교미간예조고。결론조기강복치료가용우뇌경사적치료，특별시TOAST분형중적심원성전새형화대동맥죽양경화형환자，대원기신경공능적회복기도량호효과。
Objective To clarify the prognostic differences of the early rehabilitation treatment method among different ischemic stroke subtypes.Methods 361 patients with acute ischemic stroke were collected, and were assessed with the Trial of Org 10172 in Acute Stroke Treatment ( TOAST) classification:large-vessel atherothrombotic ( LVA) , cardioembolic ( CE) , small-vessel and la-cunar infarct ( LACI) and Stroke of Other Determined Etiology&Stroke of undetermined cause ( SOD&SUD) .All the patients were di-vided into 2 groups:early rehabilitation group and control group.The prognostic factors were assessed by NIHSS,Barthel Index and Rankin at the 1 month and 6 month after rehabilitation treatment.Results On admission, Barthel Index scores of LACI patients were higher than those of CE patients.6 month after cerebral infarction onset, patients in rehabilitation groups of CE and LVA had higher Barthel Index scores than those in control group.Conclusion We should adopt rehabilitation measures in cerebral ischemic stroke, especially for CE and LVA patients, because proper rehabilitation treatment will result in excellent prognosis for long.