中国循证心血管医学杂志
中國循證心血管醫學雜誌
중국순증심혈관의학잡지
Chinese Journal of Evidence-Bases Cardiovascular Medicine
2015年
5期
628-630
,共3页
陈爱佳%肖璐%胡世蕊%冯玲
陳愛佳%肖璐%鬍世蕊%馮玲
진애가%초로%호세예%풍령
利湿降脂%熏蒸%高脂血症
利濕降脂%熏蒸%高脂血癥
리습강지%훈증%고지혈증
Draining dampness and reducing fat%Fumigation-steaming therapy%Hyperlipidemia
目的：观察利湿降脂熏蒸对湿浊痹阻型高脂血症患者血脂及中医症状的改善情况。方法连续入选2014年12月~2015年5月中国中医科学院广安门医院门诊的高脂血症患者65例，男性30例，女性35例，年龄30~75岁。随机分为熏蒸组（32例）和对照组（33例）。熏蒸组给予利湿降脂中药熏蒸治疗，对照组采用阿托伐他汀钙片（20 mg，1/晚）治疗。检测两组治疗前后血脂水平，比较疗效。比较两组中医证候和疗效。检测熏蒸组治疗前后肝肾功能指标和肌酸激酶水平。结果对照组治疗后较治疗前三酰甘油、总胆固醇均有所下降，高密度脂蛋白胆固醇上升，差异有显著统计学意义（P均＜0.01）。熏蒸组治疗后较治疗前三酰甘油、总胆固醇、低密度脂蛋白胆固醇均下降，差异有显著统计学意义（P均＜0.01）。熏蒸组中医症状疗效优于对照组，差异有统计学意义（P＜0.05）。熏蒸组临床控制、显效、有效、无效的比例为6.25%、15.6%、59.4%、18.75%，对照组显效、有效、无效的比例为12.1%、45.5%和42.4%。熏蒸组较对照组总有效率升高（81.2%vs.57.6%），差异有统计学意义（P＜0.05）。熏蒸组治疗后与治疗前比较，肝肾功能指标和肌酸激酶水平无明显变化，差异无统计学意义（P均＞0.05）。结论利湿降脂法熏蒸能有效改善血脂水平并缓解患者中医症状，并且未发生不良反应。
目的：觀察利濕降脂熏蒸對濕濁痺阻型高脂血癥患者血脂及中醫癥狀的改善情況。方法連續入選2014年12月~2015年5月中國中醫科學院廣安門醫院門診的高脂血癥患者65例，男性30例，女性35例，年齡30~75歲。隨機分為熏蒸組（32例）和對照組（33例）。熏蒸組給予利濕降脂中藥熏蒸治療，對照組採用阿託伐他汀鈣片（20 mg，1/晚）治療。檢測兩組治療前後血脂水平，比較療效。比較兩組中醫證候和療效。檢測熏蒸組治療前後肝腎功能指標和肌痠激酶水平。結果對照組治療後較治療前三酰甘油、總膽固醇均有所下降，高密度脂蛋白膽固醇上升，差異有顯著統計學意義（P均＜0.01）。熏蒸組治療後較治療前三酰甘油、總膽固醇、低密度脂蛋白膽固醇均下降，差異有顯著統計學意義（P均＜0.01）。熏蒸組中醫癥狀療效優于對照組，差異有統計學意義（P＜0.05）。熏蒸組臨床控製、顯效、有效、無效的比例為6.25%、15.6%、59.4%、18.75%，對照組顯效、有效、無效的比例為12.1%、45.5%和42.4%。熏蒸組較對照組總有效率升高（81.2%vs.57.6%），差異有統計學意義（P＜0.05）。熏蒸組治療後與治療前比較，肝腎功能指標和肌痠激酶水平無明顯變化，差異無統計學意義（P均＞0.05）。結論利濕降脂法熏蒸能有效改善血脂水平併緩解患者中醫癥狀，併且未髮生不良反應。
목적：관찰리습강지훈증대습탁비조형고지혈증환자혈지급중의증상적개선정황。방법련속입선2014년12월~2015년5월중국중의과학원엄안문의원문진적고지혈증환자65례，남성30례，녀성35례，년령30~75세。수궤분위훈증조（32례）화대조조（33례）。훈증조급여리습강지중약훈증치료，대조조채용아탁벌타정개편（20 mg，1/만）치료。검측량조치료전후혈지수평，비교료효。비교량조중의증후화료효。검측훈증조치료전후간신공능지표화기산격매수평。결과대조조치료후교치료전삼선감유、총담고순균유소하강，고밀도지단백담고순상승，차이유현저통계학의의（P균＜0.01）。훈증조치료후교치료전삼선감유、총담고순、저밀도지단백담고순균하강，차이유현저통계학의의（P균＜0.01）。훈증조중의증상료효우우대조조，차이유통계학의의（P＜0.05）。훈증조림상공제、현효、유효、무효적비례위6.25%、15.6%、59.4%、18.75%，대조조현효、유효、무효적비례위12.1%、45.5%화42.4%。훈증조교대조조총유효솔승고（81.2%vs.57.6%），차이유통계학의의（P＜0.05）。훈증조치료후여치료전비교，간신공능지표화기산격매수평무명현변화，차이무통계학의의（P균＞0.05）。결론리습강지법훈증능유효개선혈지수평병완해환자중의증상，병차미발생불량반응。
Objective To observe the effect of fumigation-steaming therapy of draining dampness and reducing fat on blood fat and TCM symptoms in patients with hyperlipidemia (type of dampness turbidity obstruction).Methods The patients (n=65, male 30, female 35 and aged from 30 to 75) were chosen from Dec. 2014 to May 2015, and randomly divided into fumigation-steaming group (n=32) and control group (n=33). The fumigation-steaming group was treated with fumigation-steaming therapy of draining dampness and reducing fat, and control group, with atorvastatin calcium tablets (20 mg, 1 piece every night). The level changes of blood fat, indexes of liver and kidney and creatine kinase were detected, and curative effects on TCM symptoms were compared in 2 groups.Results The levels of TG and TC decreased and level of HDL-C increased in control group after treatment (allP<0.01). The levels of TG, TC and LDL-C decreased in fumigation-steaming group after treatment (allP<0.01). The curative effects on TCM symptoms were better in fumigation-steaming group than those in control group (P<0.05). The clinical control rate was 6.25%, obvious effective rate was 15.6%, effective rate was 59.4% and ineffective rate was 18.75% in fumigation-steaming group, and obvious effective rate was 12.1%, effective rate was 45.5% and ineffective rate was 42.4 in control group. The total effective rate increased in fumigation-steaming group compared with control group (81.2% vs. 57.6%, P<0.05). After treatment, the indexes of liver and kidney and level of creatine kinase had no significant changes in fumigation-steaming group after treatment (allP>0.05).Conclusion The fumigation-steaming therapy of draining dampness and reducing fat can effectively ameliorate blood fat level and relieve TCM symptoms without adverse reactions.
