中国循证心血管医学杂志
中國循證心血管醫學雜誌
중국순증심혈관의학잡지
Chinese Journal of Evidence-Bases Cardiovascular Medicine
2015年
5期
650-651
,共2页
急性冠脉综合征%缺血修饰白蛋白%冠脉造影
急性冠脈綜閤徵%缺血脩飾白蛋白%冠脈造影
급성관맥종합정%결혈수식백단백%관맥조영
Acute coronary syndrome%Ischemia-modified albumin%Coronary angiography
目的：探讨急性冠脉综合征（acute coronary syndrome，ACS）患者血清缺血修饰白蛋白（ischemia-modified albumin，IMA）水平与冠脉病变程度的关系。方法入选2013年12月~2014年12月间于濮阳市安阳地区医院心血管科收住院的160例急性冠脉综合征患者，检测其血清IMA水平，同时行冠脉造影检查并分析结果。根据造影结果分为两组，B组（无冠脉狭窄或冠脉狭窄＜50％者）42例；C组：冠脉狭窄＞50％者118例。选取30例健康体检者（A组），检测其IMA水平作对照组。对C组（冠脉狭窄＞50％患者）进行亚组分析，据冠脉病变形态特点分简单病变组和复杂病变组；据冠脉Gensini积分分为三组：C1组积分＜20分，C2组20~40分、C3组＞40分。结果 C组血清IMA水平显著高于A组及B组（P＜0.05），C组亚组分析显示，随着冠脉病变程度的加重，IMA水平增加。结论 IMA水平升高与ACS患者冠脉病变严重程度有较高一致性，可做为ACS早期诊断和严重程度的参考指标。
目的：探討急性冠脈綜閤徵（acute coronary syndrome，ACS）患者血清缺血脩飾白蛋白（ischemia-modified albumin，IMA）水平與冠脈病變程度的關繫。方法入選2013年12月~2014年12月間于濮暘市安暘地區醫院心血管科收住院的160例急性冠脈綜閤徵患者，檢測其血清IMA水平，同時行冠脈造影檢查併分析結果。根據造影結果分為兩組，B組（無冠脈狹窄或冠脈狹窄＜50％者）42例；C組：冠脈狹窄＞50％者118例。選取30例健康體檢者（A組），檢測其IMA水平作對照組。對C組（冠脈狹窄＞50％患者）進行亞組分析，據冠脈病變形態特點分簡單病變組和複雜病變組；據冠脈Gensini積分分為三組：C1組積分＜20分，C2組20~40分、C3組＞40分。結果 C組血清IMA水平顯著高于A組及B組（P＜0.05），C組亞組分析顯示，隨著冠脈病變程度的加重，IMA水平增加。結論 IMA水平升高與ACS患者冠脈病變嚴重程度有較高一緻性，可做為ACS早期診斷和嚴重程度的參攷指標。
목적：탐토급성관맥종합정（acute coronary syndrome，ACS）환자혈청결혈수식백단백（ischemia-modified albumin，IMA）수평여관맥병변정도적관계。방법입선2013년12월~2014년12월간우복양시안양지구의원심혈관과수주원적160례급성관맥종합정환자，검측기혈청IMA수평，동시행관맥조영검사병분석결과。근거조영결과분위량조，B조（무관맥협착혹관맥협착＜50％자）42례；C조：관맥협착＞50％자118례。선취30례건강체검자（A조），검측기IMA수평작대조조。대C조（관맥협착＞50％환자）진행아조분석，거관맥병변형태특점분간단병변조화복잡병변조；거관맥Gensini적분분위삼조：C1조적분＜20분，C2조20~40분、C3조＞40분。결과 C조혈청IMA수평현저고우A조급B조（P＜0.05），C조아조분석현시，수착관맥병변정도적가중，IMA수평증가。결론 IMA수평승고여ACS환자관맥병변엄중정도유교고일치성，가주위ACS조기진단화엄중정도적삼고지표。
Objective To investigate the relationship between level of serum ischemia-modified albumin (IMA) and severity of coronary artery disease in patients with acute coronary syndrome (ACS).Methods The patients with ACS (n=160) were chosen and all of them were given detection of IMA level and coronary angiography (CAG). According to CAG outcomes the patients were divided into group B (without coronary artery stenosis or coronary stenosis<50%,n=42) and group C (coronary artery stenosis>50%,n=118). Other 30 healthy people were chosen and given detection of IMA level (group A). Group C was divided again, according to lesion features, into simple group and complex group, and according to Gensini integral, into group C1 (Gensini integral<20), group C2 (Gensini integral from 20 to 40) and group C3 (Gensini integral>40).Results The level of serum IMA was significantly higher in group C than that in group A and group B (P<0.05). The level of serum IMA increased as coronary lesion exacerbated.Conclusion The increase of serum IMA level is consistent to the severity of coronary artery lesion, which can be taken as a reference index for early diagnosis of ACS.
