中华临床医师杂志（电子版）
中華臨床醫師雜誌（電子版）
중화림상의사잡지（전자판）
Chinese Journal of Clinicians(Electronic Edition)
2015年
18期
3326-3328
,共3页
肝硬化,胆汁性%自身免疫抗体%临床诊断
肝硬化,膽汁性%自身免疫抗體%臨床診斷
간경화,담즙성%자신면역항체%림상진단
Liver cirrhosis%biliary%Autoimmune antibodies%Clinical diagnosis
原发性胆汁性肝硬化是一种慢性进行性胆汁淤积性自身免疫性肝病,以肝内小胆管破坏及血清高特异性抗线粒体抗体增加为特征.因其发病机制不明确,早期临床表现无明显特异性以及临床医师认识不足而容易漏诊.诊断原发性胆汁性肝硬化主要依据包括提示胆汁淤积的肝脏生化指标、抗线粒体抗体阳性以及肝脏组织病理表现为非化脓胆管炎.
原髮性膽汁性肝硬化是一種慢性進行性膽汁淤積性自身免疫性肝病,以肝內小膽管破壞及血清高特異性抗線粒體抗體增加為特徵.因其髮病機製不明確,早期臨床錶現無明顯特異性以及臨床醫師認識不足而容易漏診.診斷原髮性膽汁性肝硬化主要依據包括提示膽汁淤積的肝髒生化指標、抗線粒體抗體暘性以及肝髒組織病理錶現為非化膿膽管炎.
원발성담즙성간경화시일충만성진행성담즙어적성자신면역성간병,이간내소담관파배급혈청고특이성항선립체항체증가위특정.인기발병궤제불명학,조기림상표현무명현특이성이급림상의사인식불족이용역루진.진단원발성담즙성간경화주요의거포괄제시담즙어적적간장생화지표、항선립체항체양성이급간장조직병리표현위비화농담관염.
Primary biliary cirrhosis is a chronic progressive cholestatic autoimmune liver disease characterized by the destruction of small intrahepatic bile ducts and the presence of highly specific serum antimitochondrial antibodies. Its pathogenesis is not clear, and the early symptoms are nonspecific, easily lead to misdiagnosis. The main basis for the diagnosis of primary biliary cirrhosis include prompting liver biochemical markers of cholestasis, anti-mitochondrial antibodies and liver pathology performance of non-suppurative cholangitis.
