中华临床医师杂志(电子版)
中華臨床醫師雜誌(電子版)
중화림상의사잡지(전자판)
Chinese Journal of Clinicians(Electronic Edition)
2015年
18期
3322-3325
,共4页
肝硬化%高血压,门静脉%肠屏障
肝硬化%高血壓,門靜脈%腸屏障
간경화%고혈압,문정맥%장병장
Liver cirrhosis%Hypertension%portal%Intestinal barrier
肝硬化是各种慢性肝病发展的晚期阶段,常引起门静脉高压,对肠黏膜微循环造成破坏而导致肠黏膜屏障损伤,使肠道细菌和内毒素进入机体,引起内毒素血症及自发性腹膜炎,进一步加重肝硬化病情,形成恶性循环.因此治疗肝硬化的同时,应注重保护肠道屏障功能.
肝硬化是各種慢性肝病髮展的晚期階段,常引起門靜脈高壓,對腸黏膜微循環造成破壞而導緻腸黏膜屏障損傷,使腸道細菌和內毒素進入機體,引起內毒素血癥及自髮性腹膜炎,進一步加重肝硬化病情,形成噁性循環.因此治療肝硬化的同時,應註重保護腸道屏障功能.
간경화시각충만성간병발전적만기계단,상인기문정맥고압,대장점막미순배조성파배이도치장점막병장손상,사장도세균화내독소진입궤체,인기내독소혈증급자발성복막염,진일보가중간경화병정,형성악성순배.인차치료간경화적동시,응주중보호장도병장공능.
Liver cirrhosis is a late stage of many chronic liver disease and is often accompanied with portal hypertension which may damage intestinal mucosa microcirculation. As a result, the intestinal barrier is destroyed, which makes intestinal bacteria and endotoxin easily enter into the human body, causing endotoxemia and spontaneous bacterial peritonitis, and in return aggravating the illness of liver cirrhosis. It is a vicious circle. Therefore, the treatment of cirrhosis should include the protection of intestinal barrier function that is usually overlooked .