CAJ | 학술논문

随着发绀型先天性心脏病患儿术后的生存时间不断提升,患儿的神经智力的发育状况也愈加得到重视.先心病手术的脑损伤主要发生于体外循环,其病理生理过程均大多归结为缺氧、缺血再灌注、再氧合损伤.神经功能障碍在远期表现为运动障碍、语言发育迟缓以及认知障碍等,早期往往不易发现,具有潜在危害.研究表明,手术年龄越小远期神经智力发育就越好,而相反,在较大年龄行矫治手术的则易影响神经智力发育.
수착발감형선천성심장병환인술후적생존시간불단제승,환인적신경지력적발육상황야유가득도중시.선심병수술적뇌손상주요발생우체외순배,기병리생리과정균대다귀결위결양、결혈재관주、재양합손상.신경공능장애재원기표현위운동장애、어언발육지완이급인지장애등,조기왕왕불역발현,구유잠재위해.연구표명,수술년령월소원기신경지력발육취월호,이상반,재교대년령행교치수술적칙역영향신경지력발육.
With increasing survival rates, there is growing importance in the neurodevelopmental development among pediatric patients with cyanosis congenital heart diseases (CHD). The brain injury occurs mainly in cardiopulmonary bypass, and its pathophysiologic process is mostly due to hypoxia, ischemia-reperfusion and reoxygenation injury. Neurodevelopmental dysfunctions present in long-term motor and cognitive impairments as well as language retardation. It's hard to be discovered in the early period but it's potentially harmful. Chronological age appeared to be significantly related to the neurodevelopmental development in children with cyanosis CHD. The studies indicate that older children with CHD display an increased risk of overall, so we suggest that we'd better do operation on pediatric patients as early as possible.