中国医药导报
中國醫藥導報
중국의약도보
China Medical Herald
2015年
29期
8-12
,共5页
阻塞性睡眠呼吸暂停%心房颤动%射频消融%Meta分析
阻塞性睡眠呼吸暫停%心房顫動%射頻消融%Meta分析
조새성수면호흡잠정%심방전동%사빈소융%Meta분석
Obstructive sleep apnea%Atrial fibrillation%Cather ablation%Meta-analysis
目的：系统评价阻塞性睡眠呼吸暂停(OSA)与射频消融术后心房颤动(AF)复发的关系,为消融术后AF复发的病因探索提供依据。方法计算机检索PubMed、Embase、Cochrane图书馆、中国期刊全文数据库、维普数据库、万方数据库关于OSA与射频消融术后AF复发的队列研究,采用RevMan 5.2软件进行Meta分析。结果纳入10篇队列研究,共计1571例患者。 Meta分析结果显示：OSA组术后AF复发的风险显著高于对照组(RR =1.36,95%CI：1.25~1.48,P <0.01)。按OSA诊断方法分组,亚组分析示,柏林问卷组的术后复发风险(RR =1.46,95%CI：1.31~1.63,P<0.01)高于多导睡眠监测仪组(RR =1.28,95%CI：1.13~1.45,P=0.0001)。结论患OSA的AF患者行导管消融术后AF复发的风险较对照组高,OSA是消融术后AF复发的危险因素。
目的：繫統評價阻塞性睡眠呼吸暫停(OSA)與射頻消融術後心房顫動(AF)複髮的關繫,為消融術後AF複髮的病因探索提供依據。方法計算機檢索PubMed、Embase、Cochrane圖書館、中國期刊全文數據庫、維普數據庫、萬方數據庫關于OSA與射頻消融術後AF複髮的隊列研究,採用RevMan 5.2軟件進行Meta分析。結果納入10篇隊列研究,共計1571例患者。 Meta分析結果顯示：OSA組術後AF複髮的風險顯著高于對照組(RR =1.36,95%CI：1.25~1.48,P <0.01)。按OSA診斷方法分組,亞組分析示,柏林問捲組的術後複髮風險(RR =1.46,95%CI：1.31~1.63,P<0.01)高于多導睡眠鑑測儀組(RR =1.28,95%CI：1.13~1.45,P=0.0001)。結論患OSA的AF患者行導管消融術後AF複髮的風險較對照組高,OSA是消融術後AF複髮的危險因素。
목적：계통평개조새성수면호흡잠정(OSA)여사빈소융술후심방전동(AF)복발적관계,위소융술후AF복발적병인탐색제공의거。방법계산궤검색PubMed、Embase、Cochrane도서관、중국기간전문수거고、유보수거고、만방수거고관우OSA여사빈소융술후AF복발적대렬연구,채용RevMan 5.2연건진행Meta분석。결과납입10편대렬연구,공계1571례환자。 Meta분석결과현시：OSA조술후AF복발적풍험현저고우대조조(RR =1.36,95%CI：1.25~1.48,P <0.01)。안OSA진단방법분조,아조분석시,백림문권조적술후복발풍험(RR =1.46,95%CI：1.31~1.63,P<0.01)고우다도수면감측의조(RR =1.28,95%CI：1.13~1.45,P=0.0001)。결론환OSA적AF환자행도관소융술후AF복발적풍험교대조조고,OSA시소융술후AF복발적위험인소。
Objective To review systematically the association between obstructive sleep apnea (OSA) and atrial fibril-lation (AF) recurrence after cather ablation, and to provide evidence for etiological research of AF recurrence after cather ablation. Methods The databases of PubMed, Embase, Cochrane library, CNKI, VIP Database and Wanfang Database were retrieved for selecting cohort studies about OSA and AF recurrence after cather ablation. A Meta-analy-sis was performed by RevMan 5.2 software. Results Ten cohort studies were included with a total of 1571 patients. The results of Meta-analysis showed that risk of AF recurrence after cather ablation in patients with OSA was significantly higher than that in control group (RR =1.36, 95%CI:1.25-1.48, P<0.01). Studies were grouped according to different diagnostic tools for OSA, and subgroup analysis showed that risk of AF recurrence after cather ablation in OSA diag-nosed by Berlin questionnaire (BQ) (RR =1.46, 95%CI:1.31-1.63, P<0.01) was higher than that in OSA diagnosed by polysomnography (RR =1.28, 95%CI:1.13-1.45, P=0.0001). Conclusion Patients with OSA have a greater risk of AF recurrence than those without OSA. OSA is a risk factor of AF recurrence after cather ablation.
