海南医学
海南醫學
해남의학
Hainan Medical Journal
2015年
20期
3021-3023
,共3页
马晶晶%夏世敏%陈德林%王凤学
馬晶晶%夏世敏%陳德林%王鳳學
마정정%하세민%진덕림%왕봉학
手足口病%肠道病毒%亚型%遵义地区
手足口病%腸道病毒%亞型%遵義地區
수족구병%장도병독%아형%준의지구
Hand-foot-mouth disease%Enterovirus (EV)%Subtype%Zunyi
目的 鉴定遵义地区手足口病病毒亚型,观察其感染病毒类型特征.方法 收集2013年1~12月期间于遵义市第一人民医院就诊的疑似手足口病例样本,采用细胞分离结合逆转录-聚合酶链反应(RT-PCR)检测柯萨奇病毒A16型(CA16)、肠道病毒71型(EV71)及肠道病毒通用型(EV)的阳性率,并对所测结果进行统计分析.结果 ①在2013年度所有疑似4 680例手足口病患者的样本检测中阳性者17 47例,占37.3%.②在1 747例阳性检测标本中年龄小于2岁者895例,占所有阳性患者的51.23%;2~4岁者659例,占37.72%;4~6岁者187例,占10.70%;大于6岁者6例,占0.34%.③所有手足口病病毒阳性检出患者中CA16型阳性者38例,占2.17%;EV71型阳性者203例,占11.62%;EV型阳性者1 726例,占98.80%.结论 2013年度遵义地区手足口病主要易感人群为4岁以下儿童,病毒流行亚型以肠道病毒EV型感染为主.
目的 鑒定遵義地區手足口病病毒亞型,觀察其感染病毒類型特徵.方法 收集2013年1~12月期間于遵義市第一人民醫院就診的疑似手足口病例樣本,採用細胞分離結閤逆轉錄-聚閤酶鏈反應(RT-PCR)檢測柯薩奇病毒A16型(CA16)、腸道病毒71型(EV71)及腸道病毒通用型(EV)的暘性率,併對所測結果進行統計分析.結果 ①在2013年度所有疑似4 680例手足口病患者的樣本檢測中暘性者17 47例,佔37.3%.②在1 747例暘性檢測標本中年齡小于2歲者895例,佔所有暘性患者的51.23%;2~4歲者659例,佔37.72%;4~6歲者187例,佔10.70%;大于6歲者6例,佔0.34%.③所有手足口病病毒暘性檢齣患者中CA16型暘性者38例,佔2.17%;EV71型暘性者203例,佔11.62%;EV型暘性者1 726例,佔98.80%.結論 2013年度遵義地區手足口病主要易感人群為4歲以下兒童,病毒流行亞型以腸道病毒EV型感染為主.
목적 감정준의지구수족구병병독아형,관찰기감염병독류형특정.방법 수집2013년1~12월기간우준의시제일인민의원취진적의사수족구병례양본,채용세포분리결합역전록-취합매련반응(RT-PCR)검측가살기병독A16형(CA16)、장도병독71형(EV71)급장도병독통용형(EV)적양성솔,병대소측결과진행통계분석.결과 ①재2013년도소유의사4 680례수족구병환자적양본검측중양성자17 47례,점37.3%.②재1 747례양성검측표본중년령소우2세자895례,점소유양성환자적51.23%;2~4세자659례,점37.72%;4~6세자187례,점10.70%;대우6세자6례,점0.34%.③소유수족구병병독양성검출환자중CA16형양성자38례,점2.17%;EV71형양성자203례,점11.62%;EV형양성자1 726례,점98.80%.결론 2013년도준의지구수족구병주요역감인군위4세이하인동,병독류행아형이장도병독EV형감염위주.
Objective To investigate the virus subtypes of hand-foot-mouth disease (HFMD) in Zunyi, as well as to analyze the epidemiological features in this area. Methods Samples of suspected HFMD cases in the First People's Hospital of Zunyi from January to December in 2013 were collected. Cell separation combined with reverse transcription-polymerase chain reaction (RT-PCR) was used to detect the positive rate of coxsackie virus A16 (CA16), enterovirus 71 (EV71) and enterovirus (EV). The results was statistically analyzed. Results (1) Among the 4 680 cas-es suspected of HFMD in 2013, there were 1 747 positive infectious cases, which accounted for 37.3%. (2) Among the 1 747 positive cases, there were 895 cases of less-than-two-year-old children (accounting for 51.23%), 659 cases of 2~4-year-old children (37.72%), 187 cases of 4~6-year-old children (10.70%), and only 6 cases of more-than-6-year-old children (0.34%). (3) Among the 1 747 positive cases, there were 38 cases of CA16 subtype (accounting for 2.17%), 203 cases of EV71 subtype (11.62%), and 1 726 cases of Enterovirus (EV) subtype (98.80%). Conclusion The sus-ceptible population of HFMD in Zunyi in 2013 was the children under the age of 4. The virus subtype was mainly EV.
