CAJ | 학술논문

目的：探讨肺癌合并静脉血栓栓塞症的危险因素。方法根据是否并发静脉血栓栓塞症将315例肺癌患者分为观察组（47例）与对照组（268例），观察组确诊并发静脉血栓栓塞症，对照组未并发静脉血栓栓塞症。结果单因素分析显示，两组患者性别、年龄、体质指数、临床分期、病理类型、合并高脂血症、合并糖尿病、D二聚体、外源性激素治疗史、中心静脉置管史方面相比差异有统计学意义（P＜0．05），两组患者合并高血压、手术治疗史、靶向药物治疗史、促红细胞生成素治疗史方面相比差异无统计学意义（P＞0．05）。 Logistic回归分析显示，临床分期、病理类型、D二聚体是影响肺癌合并静脉血栓栓塞症的独立危险因素（P＜0．05）。结论影响肺癌合并静脉血栓栓塞症的危险因素较多，临床上可以采取恰当的干预措施，降低肺癌患者静脉血栓栓塞症发生率。
목적：탐토폐암합병정맥혈전전새증적위험인소。방법근거시부병발정맥혈전전새증장315례폐암환자분위관찰조（47례）여대조조（268례），관찰조학진병발정맥혈전전새증，대조조미병발정맥혈전전새증。결과단인소분석현시，량조환자성별、년령、체질지수、림상분기、병리류형、합병고지혈증、합병당뇨병、D이취체、외원성격소치료사、중심정맥치관사방면상비차이유통계학의의（P＜0．05），량조환자합병고혈압、수술치료사、파향약물치료사、촉홍세포생성소치료사방면상비차이무통계학의의（P＞0．05）。 Logistic회귀분석현시，림상분기、병리류형、D이취체시영향폐암합병정맥혈전전새증적독립위험인소（P＜0．05）。결론영향폐암합병정맥혈전전새증적위험인소교다，림상상가이채취흡당적간예조시，강저폐암환자정맥혈전전새증발생솔。
Objective To investigate the risk factors of lung cancer patients with venous thromboembolism .Methods 315 cases of lung cancer patients were divided into the observation group (47 cases)and the control group(268 cases),and the observation group was diagnosed with venous thromboembolism ,while the control group had no venous thromboembolism .Results The single factor chi-square test showed that there were obvious differences in the gender ,age,body mass index,clinical stage, pathological type,hyperlipidemia,diabetes mellitus,D-dipolymer,history of exogenous hormone therapy ,history of central venous catheterization between the 2 groups(P<0.05),while there were no obvious differences in the hypertension ,history of surgical treatment,history of targeted drug therapy,history of erythropoietin treatment between the 2 groups(P>0.05).The non-condition-al logistic regression analysis showed that clinical stage ,pathological type,D-dipolymer were risk factors of lung cancer patients with venous thromboembolism (P<0.05).Conclusion There are some risk factors which can influence lung cancer patients with venous thromboembolism ,and appropriate intervention measures are taken to reduce the incidence of venous thromboembo -lism in lung cancer patients .