CAJ | 학술논문

目的：评估淋巴结清扫手术对子宫内膜样腺癌患者生存状况的影响。方法回顾性分析70例子宫内膜样腺癌淋巴结清扫手术（ LND）患者临床资料，另选取72例非LND患者作为对照组。多因素分析总生存状况及特定生存状况的相关影响因素。结果多变量分析显示，淋巴结清扫与整体生存率和子宫特定生存率相关，其HR分别为0．81（P＜0．0001）和0．78（P＜0．0001）。淋巴结清扫11个以上者与整体生存率和子宫特定生存率相关，其HR为0．74（P＜0．0001）和0．69（P＜0．0001）。进一步多元分析证实，淋巴结清扫11个以上者与所有其他原因特定死亡率和心血管特定死亡率相关，HR分别为0．77（P＜0．0001）和0．82（P＝0．0062）。结论淋巴结清扫数量可估计子宫内膜腺癌女性的整体生存状况和子宫特定生存状况。
목적：평고림파결청소수술대자궁내막양선암환자생존상황적영향。방법회고성분석70례자궁내막양선암림파결청소수술（ LND）환자림상자료，령선취72례비LND환자작위대조조。다인소분석총생존상황급특정생존상황적상관영향인소。결과다변량분석현시，림파결청소여정체생존솔화자궁특정생존솔상관，기HR분별위0．81（P＜0．0001）화0．78（P＜0．0001）。림파결청소11개이상자여정체생존솔화자궁특정생존솔상관，기HR위0．74（P＜0．0001）화0．69（P＜0．0001）。진일보다원분석증실，림파결청소11개이상자여소유기타원인특정사망솔화심혈관특정사망솔상관，HR분별위0．77（P＜0．0001）화0．82（P＝0．0062）。결론림파결청소수량가고계자궁내막선암녀성적정체생존상황화자궁특정생존상황。
Objective To study the effects of lymph node dissection ( LND) on survival of patients with endometrial ade-nocarcinoma .Methods A retrospective analysis of clinical data of 70 cases of endometrioid adenocarcinoma treated with lymph node dissection .Related factors of overall survival and specific survival-related variables were analyzed by multivariate analysis . Results Multivariate analysis showed that LND was related with overall survival and uterus specific survival rate .Hazard ratio (HR)were 0.81(P<0.0001),and 0.78(P<0.0001),patients with LND number >11 were related with overall survival and uterus specific survival.HR were 0.74(P<0.0001),and 0.69(P<0.0001).Further multivariate analysis confirmed that pa-tients with LND number >11 were related with other causes related overall survival and cardiac-specific survival,HR were 0.77 (P<0.0001),and 0.82(P=0.0062).Conclusion LND number can predict the overall living condition and uterus specific living condition of endometrial adenocarcinoma .