CAJ | 학술논문

目的:观察血清MG7-Ag测定在卵巢癌患者诊断中的临床价值. 方法:选择卵巢恶性肿瘤组患者54例,卵巢良性肿瘤组患者67例,采用ELISA法检测全部患者血清中MG7-Ag的水平,并与同期进行体检的50例正常妇女(设为正常体检组)血清中MG7-Ag水平进行对照,对其结果进行比较. 结果:卵巢恶性肿瘤组患者的MG7-Ag水平及阳性检出率均高于良性肿瘤组及正常妇女组,组间比较差异显著(P<0. 05);而卵巢良性肿瘤组患者与正常妇女组相比,MG7-Ag的平均含量及阳性率均无显著性差异(P>0. 05);黏液性肿瘤的MG7-Ag阳性表达率为57. 14%(24/42),显著高于浆液性肿瘤31. 03%(9/29). 结论:血清MG7-Ag测定对卵巢癌患者的诊断有特异性,可作为卵巢癌早期诊断的有效指标.
목적:관찰혈청MG7-Ag측정재란소암환자진단중적림상개치. 방법:선택란소악성종류조환자54례,란소량성종류조환자67례,채용ELISA법검측전부환자혈청중MG7-Ag적수평,병여동기진행체검적50례정상부녀(설위정상체검조)혈청중MG7-Ag수평진행대조,대기결과진행비교. 결과:란소악성종류조환자적MG7-Ag수평급양성검출솔균고우량성종류조급정상부녀조,조간비교차이현저(P<0. 05);이란소량성종류조환자여정상부녀조상비,MG7-Ag적평균함량급양성솔균무현저성차이(P>0. 05);점액성종류적MG7-Ag양성표체솔위57. 14%(24/42),현저고우장액성종류31. 03%(9/29). 결론:혈청MG7-Ag측정대란소암환자적진단유특이성,가작위란소암조기진단적유효지표.
Objective:To investigate clinical value of serum MG7-Ag determination in diagnosis of ovarian cancer. Methods:54 patients with ovarian malignant tumor and 67 patients with benign ovarian tumor were selected. Serum MG7-Ag levels in all patients were detected by ELISA method. Meanwhile, 50 normal females underwent physical examination were included in this study, as the controls and their serum MG7-Ag levels were also detected. The detection results were compared. Results:The serum MG7-Ag level and positive rate in ovarian malignant tumor group were significantly higher than those in benign tumor group and normal control group (P<0. 05). There was no significant difference in the serum MG7-Ag level and positive rate between benign tumor group and normal control group (P>0. 05). The positive expression rate of MG7-Ag in mucinous tumor was 57. 14% (24/42), which was significantly higher than that in serous tumor (31. 03%, 9/29). Conclusions:Serum MG7-Ag level is a specific index for the diagnosis of ovarian cancer, and can be used as the effective index in early diagnosis of ovarian cancer.