CAJ | 학술논문

目的：探讨复方康复灵对体部伽玛刀治疗非小细胞肺癌急性放射反应的防护作用。方法选取接受体部伽玛刀治疗的非小细胞肺癌患者107例，随机分为观察组（55例）和对照组（52例）。观察组在放疗开始后给予复方康复灵口服，疗程1个月，比较两组的急性放射反应。结果治疗后观察组患者外周血白细胞下降发生率为5．5％，对照组为21．2％（ P＜0．05）；观察组急性放射性肺炎发生率为16．4％，对照组为15．4％（P＞0．05）；观察组急性放射性食管炎发生率为25．5％，对照组为28．8％（P＞0．05）。结论复方康复灵对非小细胞肺癌患者接受体部伽玛刀治疗引起的外周血白细胞下降具有较好的预防作用，值得临床推广。
목적：탐토복방강복령대체부가마도치료비소세포폐암급성방사반응적방호작용。방법선취접수체부가마도치료적비소세포폐암환자107례，수궤분위관찰조（55례）화대조조（52례）。관찰조재방료개시후급여복방강복령구복，료정1개월，비교량조적급성방사반응。결과치료후관찰조환자외주혈백세포하강발생솔위5．5％，대조조위21．2％（ P＜0．05）；관찰조급성방사성폐염발생솔위16．4％，대조조위15．4％（P＞0．05）；관찰조급성방사성식관염발생솔위25．5％，대조조위28．8％（P＞0．05）。결론복방강복령대비소세포폐암환자접수체부가마도치료인기적외주혈백세포하강구유교호적예방작용，치득림상추엄。
Objective To investigate the protective effect of compound Kangfulin on acute radiation reaction of the body gam-ma knife in treatment of non-small cell lung cancer.Methods To select 107 patients who received the body gamma knife treatment of non-small cell lung cancer, then divided them into observation group (55 cases)and control group (52 cases) randomly.The observa-tion group was given the compound Kangfulin for a month after the beginning of radiotherapy, and compared the acute radio injury be-tween two groups.Results The decreasing incidence of peripheral blood leukocytes in observation group was 5.5%and control group was 21.2%.The difference was statistically significant (P<0.05).The incidence of acute radiation pneumonitis in observation group was 16.4%and control group was 15.4%.The difference was not statistically significant (P>0.05).The incidence of acute radia-tion esophagitis in observation group was 25.5%and control group was 28.8%.The difference was not statistically significant ( P>0.05).Conclusion The compound kangfulin has a good preventive effect on the decreasing Peripheral blood leukocytes of the non-small cell lung cancer patients who have received body gamma knife treatment.It was worthy of promotion in clinic.