CAJ | 학술논문

目的研究不同糖代谢状况缺血性脑卒中患者的糖化血红蛋白水平与脑动脉病变程度的关系。方法选取2013年6月～2015年6月唐山市工人医院收治的缺血性脑卒中患者120例，根据糖代谢情况分为正常组（n=20）、异常组（n=65）、糖尿病组（n=35），比较三组的一般资料、分析HbAlc水平、脑动脉病变危险因素、脑动脉病变部位及支数。结果三组患者性别、高血压、吸烟、TG、Hcy等方面比较，差异无统计学意义（P＞0.05），三组患者中饮酒、冠心病、HbAlc、TC、HDL-C、LDL-C比较，差异有统计学意义（P＜0.05）；三组患者中，正常组脑血管狭窄以轻度为主，前循环多见，单支受累血管多。糖代谢异常组和糖尿病组患者脑血管狭窄以中、重度为主，前后循环和多支受累为主（P＜0.05）。结论不同糖代谢水平影响脑血管病变， HbAlc水平影响脑动脉病变程度、病变部位和病变支数，是影响脑动脉病变的重要危险因素。
목적연구불동당대사상황결혈성뇌졸중환자적당화혈홍단백수평여뇌동맥병변정도적관계。방법선취2013년6월～2015년6월당산시공인의원수치적결혈성뇌졸중환자120례，근거당대사정황분위정상조（n=20）、이상조（n=65）、당뇨병조（n=35），비교삼조적일반자료、분석HbAlc수평、뇌동맥병변위험인소、뇌동맥병변부위급지수。결과삼조환자성별、고혈압、흡연、TG、Hcy등방면비교，차이무통계학의의（P＞0.05），삼조환자중음주、관심병、HbAlc、TC、HDL-C、LDL-C비교，차이유통계학의의（P＜0.05）；삼조환자중，정상조뇌혈관협착이경도위주，전순배다견，단지수루혈관다。당대사이상조화당뇨병조환자뇌혈관협착이중、중도위주，전후순배화다지수루위주（P＜0.05）。결론불동당대사수평영향뇌혈관병변， HbAlc수평영향뇌동맥병변정도、병변부위화병변지수，시영향뇌동맥병변적중요위험인소。
ObjectiveTo study the relationship between the level of glycosylated hemoglobin and cerebral arterial lesions in patients with ischemic stroke with different glucose metabolism.Methods 120 cases of ischemic stroke patients were chosen from June 2013 to June 2015 in Tangshan workers hospital, according to glucose metabolism is divided into normal group (n=20) and abnormal group (n=65), diabetes group (n=35). To analysis of HbA1c level, risk factors for cerebral artery disease, cerebral artery lesion sites and count of the three groups were compared. ResultsThere were no significant differences in gender, hypertension, smoking, TG, Hcy among the three groups (P>0.05), the differences were statistically signiifcant with alcohol, coronary heart disease, TC, HDL-C, HbAlc, LDL-C In the three groups of patients (P<0.05). In the patients with abnormal glucose metabolism and diabetes mellitus, cerebral blood vessel stenosis was dominated by moderate and severe cerebral artery stenosis, and the main was the main and the most affected (P<0.05).Conclusion Different levels of glucose metabolism affect cerebral vascular lesions and HbAlc level of cerebral artery stenosis, the location of the lesion and lesion count is affect brain artery disease are important risk factors.