CAJ | 학술논문

开展药物经济学评价所需的数据可以来自于随机对照试验（RCTs）和真实世界研究。真实世界研究的设计原则很好地满足了药物经济学评价的需求，但其研究设计和分析方法与RCTs有很大差异。本研究探讨了真实世界研究的相关定义及其与RCTs的区别和联系，以及在应用真实世界研究开展药物经济学评价时所需注意的相关问题，以期为研究者提供一定借鉴。
개전약물경제학평개소수적수거가이래자우수궤대조시험（RCTs）화진실세계연구。진실세계연구적설계원칙흔호지만족료약물경제학평개적수구，단기연구설계화분석방법여RCTs유흔대차이。본연구탐토료진실세계연구적상관정의급기여RCTs적구별화련계，이급재응용진실세계연구개전약물경제학평개시소수주의적상관문제，이기위연구자제공일정차감。
Data needed for pharmacoeconomic evaluation may be obtained from randomized controled trials (RCTs)and from real world study.The design principles of real world study wel satisfied the need of pharmacoe- conomic evaluation.Meanwhile,its study design and analysis methods are quite different from RCTs’.This study discussed the difference and relationship between RCTs and real world study,as wel the related issues should be paid attention to when conduct pharmacoeconomic evaluation in real world study design.