CAJ | 학술논문

目的：探讨Q-开关Nd：YAG激光联合强脉冲光治疗黄褐斑的临床疗效。方法随机选取2014年8月～2015年6月我院收治的88例黄褐斑患者作为研究对象，采用回顾分析法，将其分为治疗组（41例）、联合组（32例）与对照组（15例），治疗组主要采用Q-开关激光进行治疗，联合组主要采用Q-开关激光与强脉冲光联合治疗，对照组主要采用中药祛斑面膜进行治疗，对三组患者的临床效果进行比较。结果联合组总有效率为75.0%，治疗组总有效率为51.21%，对照组总有效率为46.66%，通过三组的临床效果比较，联合组和治疗组均取得了良好的效果，三组患者的临床效果比较差异具有统计学意义（P＜0.05）。其中联合组有1例患者发生色素沉着，无瘢痕，治疗组有3例发生色素沉着，对照组有5例发生皮肤过敏，三组患者的不良反应比较具有统计学意义（P＜0.05）。结论对黄褐斑患者主要使用Q-开关激光与强脉冲光联合治疗，具有副作用少、安全可靠等特点，在临床中取得了良好的效果。
목적：탐토Q-개관Nd：YAG격광연합강맥충광치료황갈반적림상료효。방법수궤선취2014년8월～2015년6월아원수치적88례황갈반환자작위연구대상，채용회고분석법，장기분위치료조（41례）、연합조（32례）여대조조（15례），치료조주요채용Q-개관격광진행치료，연합조주요채용Q-개관격광여강맥충광연합치료，대조조주요채용중약거반면막진행치료，대삼조환자적림상효과진행비교。결과연합조총유효솔위75.0%，치료조총유효솔위51.21%，대조조총유효솔위46.66%，통과삼조적림상효과비교，연합조화치료조균취득료량호적효과，삼조환자적림상효과비교차이구유통계학의의（P＜0.05）。기중연합조유1례환자발생색소침착，무반흔，치료조유3례발생색소침착，대조조유5례발생피부과민，삼조환자적불량반응비교구유통계학의의（P＜0.05）。결론대황갈반환자주요사용Q-개관격광여강맥충광연합치료，구유부작용소、안전가고등특점，재림상중취득료량호적효과。
Objective To study the Q - switching Nd: YAG laser in combination with curative effect pulsed light treatment of chloasma. Methods88 cases of chloasma patients in our hospital from August 2014~June 2015, they were divided into the treatment group (41 cases), the joint group (32 cases) and control group (15 cases), the Q-switching laser treatment, joint group mainly adopts Q-switchingto compare the clinical effect of three groups of patients.Results The total effective rate was 75.0%, effective rate was 51.21%, total effective rate was 46.66%, clinical effect comparison of three groups of patients with statistical significance (P<0.05). The joint group of pigmentation occurred in 1 patients, no scar, the treatment group with 3 cases of control group have 5 cases clinical groups of patients with statistical signiifcance (P<0.05). Conclusion The main use in patients with chloasma Q-switching combination treatment safe and reliable, good results have been achieved in the clinical.