CAJ | 학술논문

目的了解本地区皮肤性病门诊患者单纯疱疹病毒(HSV)的感染情况.方法选取2013-2014年就诊于本院皮肤性病门诊的974例初诊疑似生殖器疱疹患者,采用酶联免疫法(ELISA)检测血清HSV1和HSV2的IgG、IgM抗体.结果 974例疑似生殖器疱疹患者HSV1-IgG和IgM的检出率分别为85.1%和2.0%, HSV2-IgG和IgM检出率分别为23.3%和5.4%.其中306例有典型生殖器疱疹症状者HSV1-IgG和IgM的感染率分别为84.0%和3.3%,HSV2-IgG和IgM感染率分别为44.8%和6.2%.疑似生殖器疱疹患者不同年龄组比较,除HSV1-IgM差异无统计学意义外,其余抗体差异均有统计学意义(P<0.05);其中HSV2-IgG以40~49岁检出率较高.结论本地区皮肤性病门诊患者HSV抗体检出率较高,生殖器疱疹主要由HSV2感染引起;女性HSV2感染率高于男性;且存在HSV的混合感染及与其他性传播疾病的复杂感染.
목적 료해본지구피부성병문진환자단순포진병독(HSV)적감염정황.방법 선취2013-2014년취진우본원피부성병문진적974례초진의사생식기포진환자,채용매련면역법(ELISA)검측혈청HSV1화HSV2적IgG、IgM항체.결과 974례의사생식기포진환자HSV1-IgG화IgM적검출솔분별위85.1%화2.0%, HSV2-IgG화IgM검출솔분별위23.3%화5.4%.기중306례유전형생식기포진증상자HSV1-IgG화IgM적감염솔분별위84.0%화3.3%,HSV2-IgG화IgM감염솔분별위44.8%화6.2%.의사생식기포진환자불동년령조비교,제HSV1-IgM차이무통계학의의외,기여항체차이균유통계학의의(P<0.05);기중HSV2-IgG이40~49세검출솔교고.결론 본지구피부성병문진환자HSV항체검출솔교고,생식기포진주요유HSV2감염인기;녀성HSV2감염솔고우남성;차존재HSV적혼합감염급여기타성전파질병적복잡감염.
Objective To explore the infections of herpes simplex virus (HSV) in the outpatients of skin and sexually transmitted disease in Panyu District of Guangzhou. Methods Serologic detection of herpes simplex virus an-tibody (IgG and IgM of HSV1 and HSV2) was performed by ELISA in 974 suspected patients with genital herpes from 2013 to 2014. Results In the 974 suspected patients, the positive rate of HSV1-IgG and HSV1-IgM were 85.1%and 2.0%, respectively. The positive rate of HSV2-IgG and HSV2-IgM were 23.3%and 5.4%, respectively. Among 306 pa-tients with typical genital herpes, the infection rates of HSV1-IgG and HSV1-IgM were 84.0%and 3.3%, and the infec-tion rates of HSV2-IgG and HSV2-IgM were 44.8%and 6.2%, respectively. There were differences in HSV antibody positive rates between different age groups of suspected patients, except the HSV1-IgM. Among different age groups, 40~49 was higher than others in the positive rate of HSV2-IgG. Conclusion There is a high positive detection rate of HSV antibody from the skin and sexually transmitted disease clinic in Panyu District of Guangzhou. Genital herpes is mainly caused by HSV2 infection. The infection rate of HSV2 in women is higher than that in men with suspected or typical genital herpes cases. Mixed infection with other sexually transmitted diseases and compound infections should be detected in some patients.