海南医学
海南醫學
해남의학
Hainan Medical Journal
2015年
19期
2916-2918
,共3页
周练兴%张雄伟%陈强文%吴汉潮%李中%余承洸%丘成%刘国健%张荣隆%张木华%王强
週練興%張雄偉%陳彊文%吳漢潮%李中%餘承洸%丘成%劉國健%張榮隆%張木華%王彊
주련흥%장웅위%진강문%오한조%리중%여승광%구성%류국건%장영륭%장목화%왕강
托特罗定%膀胱过度活动症%输尿管支架管%双J管
託特囉定%膀胱過度活動癥%輸尿管支架管%雙J管
탁특라정%방광과도활동증%수뇨관지가관%쌍J관
Tolterodine%Overactive bladder%Ureteral stent%Double J tube
目的 探讨托特罗定干预输尿管双J管留置后膀胱过度活动症的疗效及安全性.方法 2014年4~12月在我院泌尿外科住院术后输尿管留置双J管患者126例,随机分成两组,每组各63例.观察组术后拔除尿管日开始口服托特罗定2 mg/d连续6周至拔除双J管;对照组无相关辅助治疗.两组患者均于术前1 d及术后6周拔除双J管前完成OABSS问卷表,比较其带管期间尿急评分和OABSS评分情况,记录观察组治疗期间药物不良反应发生情况.结果 观察组尿急评分为(1.6±0.8)分,对照组为(3.5±1.6)分,两组比较差异具有统计学意义(P<0.01);治疗组OABSS评分为(3.4±1.3)分,对照组为(8.2±3.6)分,两组比较差异具有统计学意义(P<0.01).观察组治疗期间药物总不良反应发生率为14.3%.结论 托特罗定干预输尿管双J管留置后膀胱过度活动症安全、有效,可用于输尿管双J管留置术后患者,改善生活质量.
目的 探討託特囉定榦預輸尿管雙J管留置後膀胱過度活動癥的療效及安全性.方法 2014年4~12月在我院泌尿外科住院術後輸尿管留置雙J管患者126例,隨機分成兩組,每組各63例.觀察組術後拔除尿管日開始口服託特囉定2 mg/d連續6週至拔除雙J管;對照組無相關輔助治療.兩組患者均于術前1 d及術後6週拔除雙J管前完成OABSS問捲錶,比較其帶管期間尿急評分和OABSS評分情況,記錄觀察組治療期間藥物不良反應髮生情況.結果 觀察組尿急評分為(1.6±0.8)分,對照組為(3.5±1.6)分,兩組比較差異具有統計學意義(P<0.01);治療組OABSS評分為(3.4±1.3)分,對照組為(8.2±3.6)分,兩組比較差異具有統計學意義(P<0.01).觀察組治療期間藥物總不良反應髮生率為14.3%.結論 託特囉定榦預輸尿管雙J管留置後膀胱過度活動癥安全、有效,可用于輸尿管雙J管留置術後患者,改善生活質量.
목적 탐토탁특라정간예수뇨관쌍J관류치후방광과도활동증적료효급안전성.방법 2014년4~12월재아원비뇨외과주원술후수뇨관류치쌍J관환자126례,수궤분성량조,매조각63례.관찰조술후발제뇨관일개시구복탁특라정2 mg/d련속6주지발제쌍J관;대조조무상관보조치료.량조환자균우술전1 d급술후6주발제쌍J관전완성OABSS문권표,비교기대관기간뇨급평분화OABSS평분정황,기록관찰조치료기간약물불량반응발생정황.결과 관찰조뇨급평분위(1.6±0.8)분,대조조위(3.5±1.6)분,량조비교차이구유통계학의의(P<0.01);치료조OABSS평분위(3.4±1.3)분,대조조위(8.2±3.6)분,량조비교차이구유통계학의의(P<0.01).관찰조치료기간약물총불량반응발생솔위14.3%.결론 탁특라정간예수뇨관쌍J관류치후방광과도활동증안전、유효,가용우수뇨관쌍J관류치술후환자,개선생활질량.
Objective To investigate the curative effect and safety of Tolterodine intervention for overactive bladder after retaining double J tuble in ureter. Methods One hundred and twenty-six patients in Department of Urol-ogy between April 2014 and December 2014 with retained double J tube in ureter were randomly divided into two groups:control group (n=63) and treatment group (n=63). Patients in the treatment group after catheter removal day were given oral Tolterodine 2 mg per day consecutively for 6 weeks until the removal of double J tube. Patients in the control group did not receive any relevant auxiliary treatment. The urgency score and overactive bladder symptom score (OABSS, investigated one day before surgery and 6 weeks after surgery) were compared between the two groups, and the adverse reactions in the treatment group were recorded. Results The urgency score in treatment group and in the control group were (1.6±0.8) and (3.5±1.6), respectively, with statistically significant differences be-tween the two groups (P<0.01). The OABSS score in treatment group and in the control group were (3.4 ± 1.3) and (8.2 ± 3.66), respectively, and there was statistically significant differences (P<0.01). Conclusion Tolterodine inter-vention for overactive bladder after retaining double J tuble is safe and effective, which can help improve the quality of life for patients.
