海南医学
海南醫學
해남의학
Hainan Medical Journal
2015年
19期
2934-2938
,共5页
卵巢交界性肿瘤%保留生育功能%附件切除术%囊肿剥除术%Meta分析
卵巢交界性腫瘤%保留生育功能%附件切除術%囊腫剝除術%Meta分析
란소교계성종류%보류생육공능%부건절제술%낭종박제술%Meta분석
Borderline ovarian tumor%Fertility sparing%Salpingo-oophorectomy%Cystectomy%Meta-analysis
目的 比较卵巢交界性肿瘤患者行保留生育功能的单侧附件切除术(USO)与囊肿剥除术(CYS)发生术中囊肿破裂、术后复发与术后妊娠情况的差异.方法 系统检索PubMed、Embase、Cochrane Library及全中文数据库,搜索卵巢交界性肿瘤、保留生育功能手术、单侧附件切除术与囊肿剥除术的前瞻性及回顾性研究,阅读全文,提取资料中对照试验,利用Review Manager 5.2进行系统评价.结果 最终纳入6篇文献,483例患者.Meta分析结果显示:①USO术中囊肿破裂率较CYS低,RR=0.73,P=0.06,95%CI(0.52~1.01),差异无统计学意义.②术后复发率USO较CYS低,RR=0.48,P=0.004,95%CI(0.32~0.72),差异有统计学意义.③术后共144例患者有妊娠愿望,其中USO组98例,59例成功妊娠;CYS组56例,29例成功妊娠,OR=1.26,P=0.54,95%CI(0.81, 1.48),差异无统计学意义.结论 BOT患者采用单侧附件切除术及囊肿剥除术均有一定的术后妊娠率,但单侧附件切除术较囊肿剥除术更安全.
目的 比較卵巢交界性腫瘤患者行保留生育功能的單側附件切除術(USO)與囊腫剝除術(CYS)髮生術中囊腫破裂、術後複髮與術後妊娠情況的差異.方法 繫統檢索PubMed、Embase、Cochrane Library及全中文數據庫,搜索卵巢交界性腫瘤、保留生育功能手術、單側附件切除術與囊腫剝除術的前瞻性及迴顧性研究,閱讀全文,提取資料中對照試驗,利用Review Manager 5.2進行繫統評價.結果 最終納入6篇文獻,483例患者.Meta分析結果顯示:①USO術中囊腫破裂率較CYS低,RR=0.73,P=0.06,95%CI(0.52~1.01),差異無統計學意義.②術後複髮率USO較CYS低,RR=0.48,P=0.004,95%CI(0.32~0.72),差異有統計學意義.③術後共144例患者有妊娠願望,其中USO組98例,59例成功妊娠;CYS組56例,29例成功妊娠,OR=1.26,P=0.54,95%CI(0.81, 1.48),差異無統計學意義.結論 BOT患者採用單側附件切除術及囊腫剝除術均有一定的術後妊娠率,但單側附件切除術較囊腫剝除術更安全.
목적 비교란소교계성종류환자행보류생육공능적단측부건절제술(USO)여낭종박제술(CYS)발생술중낭종파렬、술후복발여술후임신정황적차이.방법 계통검색PubMed、Embase、Cochrane Library급전중문수거고,수색란소교계성종류、보류생육공능수술、단측부건절제술여낭종박제술적전첨성급회고성연구,열독전문,제취자료중대조시험,이용Review Manager 5.2진행계통평개.결과 최종납입6편문헌,483례환자.Meta분석결과현시:①USO술중낭종파렬솔교CYS저,RR=0.73,P=0.06,95%CI(0.52~1.01),차이무통계학의의.②술후복발솔USO교CYS저,RR=0.48,P=0.004,95%CI(0.32~0.72),차이유통계학의의.③술후공144례환자유임신원망,기중USO조98례,59례성공임신;CYS조56례,29례성공임신,OR=1.26,P=0.54,95%CI(0.81, 1.48),차이무통계학의의.결론 BOT환자채용단측부건절제술급낭종박제술균유일정적술후임신솔,단단측부건절제술교낭종박제술경안전.
Objective To evaluate the efficacy and safety of unilateral salpingo-oophorectomy (USO) and cystectomy (CYS) as fertility-sparing therapy in treating borderline ovarian tumor (BOT) by comparing their rates of cyst rupture during operation, postoperative recurrence and postoperative pregnancy. Methods Prospective and retro-spective studies on BOT, fertility-sparing surgery, USO and CYS were searched from database such as PubMed, Co-charane Library, EMbase, CNKI, VIP and Wanfang. Cinical controlled trails (CCTs) were extracted from these studies, and meta-analysis was performed using Review Manager 5.2 software. Results Six studies involving 483 patients were included. The results of meta-analysis showed that:(1) The rate of cyst rupture during operation of USO was low-er than that of CYS, with RR=0.73, P=0.06, 95%CI(0.52, 1.01), and the difference was not statistically significant. (2) The postoperative recurrence rate of USO was lower than that of CYS. RR=0.48, P=0.004, 95%CI(0.32, 0.72), and the difference was statistically significant. (3) After operation, a total of 144 patients tried to conceive, with 98 patients in the USO group and 56 in the CYS group. And it turned out that there were 59 successful cases in the USO group and 29 in the CYS group, with OR=1.26, P=0.54, 95%CI(0.81, 1.48), and the difference was not statistically significant. Conclusion Both USO and CYS can bring BOT patients chances of pregnancy, while USO tended to be safer.
