国际医药卫生导报
國際醫藥衛生導報
국제의약위생도보
International Medicine and Health Guidance News
2015年
19期
2889-2892
,共4页
右美托咪定%高血压%血流动力学%镇痛评分%躁动情况
右美託咪定%高血壓%血流動力學%鎮痛評分%躁動情況
우미탁미정%고혈압%혈류동역학%진통평분%조동정황
Dexmedetomidine%Hypertension%Hemodynamics%Analgesic score%Restlessness
目的 探讨右美托咪定静脉麻醉对高血压患者恢复期血流动力学、镇痛评分及躁动情况的影响.方法 将行气管插管全麻开腹手术的高血压患者98例随机分为研究组(n=49)和对照组(n=49).研究组右美托咪定静脉麻醉,对照组靶控输入丙泊酚.统计两组恢复期血流动力学、镇痛评分、拔管质量及躁动情况.结果 研究组拔管后10 min镇静评分明显高于对照组,差异有统计学意意义(P<0.05);两组治疗前HR、SBP、DBP对比差异无统计学意义(P>0.05);研究组T2、T3、T4时刻HR、BP、DBP明显低于同时刻对照组,差异有统计学意义(P<0.05);研究组拔管质量明显优于对照组,差异有统计学意义(P<0.05);研究组术后躁动发生率明显低于对照组,差异有统计学意义(P<0.05).结论 右美托咪定用于高血压全麻患者恢复期具有稳定血流动力学的作用,拔管质量好,镇痛效果好,且术后躁动少,是一种理想的高血压全麻患者手术麻醉药物.
目的 探討右美託咪定靜脈痳醉對高血壓患者恢複期血流動力學、鎮痛評分及躁動情況的影響.方法 將行氣管插管全痳開腹手術的高血壓患者98例隨機分為研究組(n=49)和對照組(n=49).研究組右美託咪定靜脈痳醉,對照組靶控輸入丙泊酚.統計兩組恢複期血流動力學、鎮痛評分、拔管質量及躁動情況.結果 研究組拔管後10 min鎮靜評分明顯高于對照組,差異有統計學意意義(P<0.05);兩組治療前HR、SBP、DBP對比差異無統計學意義(P>0.05);研究組T2、T3、T4時刻HR、BP、DBP明顯低于同時刻對照組,差異有統計學意義(P<0.05);研究組拔管質量明顯優于對照組,差異有統計學意義(P<0.05);研究組術後躁動髮生率明顯低于對照組,差異有統計學意義(P<0.05).結論 右美託咪定用于高血壓全痳患者恢複期具有穩定血流動力學的作用,拔管質量好,鎮痛效果好,且術後躁動少,是一種理想的高血壓全痳患者手術痳醉藥物.
목적 탐토우미탁미정정맥마취대고혈압환자회복기혈류동역학、진통평분급조동정황적영향.방법 장행기관삽관전마개복수술적고혈압환자98례수궤분위연구조(n=49)화대조조(n=49).연구조우미탁미정정맥마취,대조조파공수입병박분.통계량조회복기혈류동역학、진통평분、발관질량급조동정황.결과 연구조발관후10 min진정평분명현고우대조조,차이유통계학의의의(P<0.05);량조치료전HR、SBP、DBP대비차이무통계학의의(P>0.05);연구조T2、T3、T4시각HR、BP、DBP명현저우동시각대조조,차이유통계학의의(P<0.05);연구조발관질량명현우우대조조,차이유통계학의의(P<0.05);연구조술후조동발생솔명현저우대조조,차이유통계학의의(P<0.05).결론 우미탁미정용우고혈압전마환자회복기구유은정혈류동역학적작용,발관질량호,진통효과호,차술후조동소,시일충이상적고혈압전마환자수술마취약물.
Objective To investigate the influence of anesthesia by intravenously given dexmedetomidine on the hemodynamics, analgesic score, and restlessness in hypertensive patients during recovery period.Methods 98 hypertensive patients undergoing endotracheal intubation laparotomy were randomly divided into a research group (n=49) and a control group (n=49).The research group were intravenously given dexmedetomidine for anesthesia and the control group target-controlledly input propofol.The hemodynamics, analgesic score, extubation quality, and restlessness during recovery period in both groups were statistically analyzed.Results The analgesic score was significantly higher in the research group than in the control group 10 min after extubation, with a statistical difference (P>0.05).Before the treatment, there were no statistical differences in HR, SBP, and DBP between these two groups (P<0.05).At T2, T3, and T4, HR, BP, and DBP were significantly lower in the research group than in the control group, with statistical differences (P<0.05).The extubation quality was significantly higher and the incidence of restlessness was significantly lower in the research group than in the control group, with statistical differences (P<0.05).Conclusions Anesthesia by dexmedetomidine for hypertensive patients during recovery period can stabilize hemodynamics and decrease the incidence of restlessness after operation and has good extubation quality and good analgesic effect, so it is an ideal operative anesthesia drug for hypertensive patients.
