海南医学
海南醫學
해남의학
Hainan Medical Journal
2015年
19期
2824-2827
,共4页
中药%养阴通络汤%西药%糖尿病脑梗死%疗效%血液流变学%血糖%血脂
中藥%養陰通絡湯%西藥%糖尿病腦梗死%療效%血液流變學%血糖%血脂
중약%양음통락탕%서약%당뇨병뇌경사%료효%혈액류변학%혈당%혈지
Traditional Chinese medicine (TCM)%Yangyin Tongluo decoction%Western medicine%Diabetic cerebral infarction%Curative effect%Hemorheology%Blood sugar%Blood lipids
目的 探讨中药养阴通络汤联合西药治疗糖尿病脑梗死患者的疗效及其对患者血液流变学、血糖和血脂的影响.方法 将2012年1月至2014年7月期间在我院接受诊治的107例患者按照随机数表法分为对照组53例和观察组54例.对照组采用常规西药治疗,观察组在对照组常规西药治疗基础上结合中药养阴通络汤治疗.比较两组患者的血液流变学指标、血糖和血脂水平、神经功能缺损评分及临床疗效.结果 观察组总有效率为90.74%,明显高于对照组的69.81%,差异有统计学意义(P<0.05);两组患者的神经功能缺损评分和血糖水平治疗后均较治疗前明显降低,且观察组降低较对照组更明显,差异均有统计学意义(P<0.05);两组高切全血黏度、低切全血黏度、红细胞压积、血浆黏度治疗后均较治疗前明显减少,且观察组降低较对照组更明显,差异均有统计学意义(P<0.05);两组低密度脂蛋白胆固醇(LDL-C)、甘油三酯(TG)、总胆固醇(TC)治疗后均较治疗前显著降低,且观察组降低较对照组更明显,差异均有统计学意义(P<0.05);两组治疗期间均未见明显不良反应发生.结论 中药养阴通络汤联合西药治疗糖尿病脑梗死疗效显著,其可明显改善患者血液流变学和血脂水平,降低血糖,无明显不良反应,具有重要临床应用价值.
目的 探討中藥養陰通絡湯聯閤西藥治療糖尿病腦梗死患者的療效及其對患者血液流變學、血糖和血脂的影響.方法 將2012年1月至2014年7月期間在我院接受診治的107例患者按照隨機數錶法分為對照組53例和觀察組54例.對照組採用常規西藥治療,觀察組在對照組常規西藥治療基礎上結閤中藥養陰通絡湯治療.比較兩組患者的血液流變學指標、血糖和血脂水平、神經功能缺損評分及臨床療效.結果 觀察組總有效率為90.74%,明顯高于對照組的69.81%,差異有統計學意義(P<0.05);兩組患者的神經功能缺損評分和血糖水平治療後均較治療前明顯降低,且觀察組降低較對照組更明顯,差異均有統計學意義(P<0.05);兩組高切全血黏度、低切全血黏度、紅細胞壓積、血漿黏度治療後均較治療前明顯減少,且觀察組降低較對照組更明顯,差異均有統計學意義(P<0.05);兩組低密度脂蛋白膽固醇(LDL-C)、甘油三酯(TG)、總膽固醇(TC)治療後均較治療前顯著降低,且觀察組降低較對照組更明顯,差異均有統計學意義(P<0.05);兩組治療期間均未見明顯不良反應髮生.結論 中藥養陰通絡湯聯閤西藥治療糖尿病腦梗死療效顯著,其可明顯改善患者血液流變學和血脂水平,降低血糖,無明顯不良反應,具有重要臨床應用價值.
목적 탐토중약양음통락탕연합서약치료당뇨병뇌경사환자적료효급기대환자혈액류변학、혈당화혈지적영향.방법 장2012년1월지2014년7월기간재아원접수진치적107례환자안조수궤수표법분위대조조53례화관찰조54례.대조조채용상규서약치료,관찰조재대조조상규서약치료기출상결합중약양음통락탕치료.비교량조환자적혈액류변학지표、혈당화혈지수평、신경공능결손평분급림상료효.결과 관찰조총유효솔위90.74%,명현고우대조조적69.81%,차이유통계학의의(P<0.05);량조환자적신경공능결손평분화혈당수평치료후균교치료전명현강저,차관찰조강저교대조조경명현,차이균유통계학의의(P<0.05);량조고절전혈점도、저절전혈점도、홍세포압적、혈장점도치료후균교치료전명현감소,차관찰조강저교대조조경명현,차이균유통계학의의(P<0.05);량조저밀도지단백담고순(LDL-C)、감유삼지(TG)、총담고순(TC)치료후균교치료전현저강저,차관찰조강저교대조조경명현,차이균유통계학의의(P<0.05);량조치료기간균미견명현불량반응발생.결론 중약양음통락탕연합서약치료당뇨병뇌경사료효현저,기가명현개선환자혈액류변학화혈지수평,강저혈당,무명현불량반응,구유중요림상응용개치.
Objective To investigate the curative effect of traditional Chinese medicine combined with western medicine in the treatment of diabetic cerebral infarction and the effect on hemorheology, blood sugar, blood lipids. Methods One hundred and seven patients with diabetic cerebral infarction treated in our hospital from 2012 to 2014 were randomly divided into the control group (n=53) and observation group (n=54). The control group was treated with conventional western medicine, while the observation group was treated with traditional Chinese medi-cine (TCM, Yangyin Tongluo decoction) on the basis of the treatment of the control group. The hemorheology, blood sugar levels, blood lipid levels, neurological function defect scale and efficacy were compared between the two groups. Results The total effective rate of the observation group (90.74%) was significantly higher than that of the control group (69.81%), with statistically significant difference (P<0.05). After the treatment, the neurological func-tion defect scale and the blood sugar levels in two groups were significantly lower than those before treatment, and the decreases in the observation group were more obvious than those in the control group, with statistically significant differ-ence (P<0.05). The high shear whole blood viscosity, low shear whole blood viscosity, hematocrit, plasma viscosity after treatment in the two groups were significantly lower than those before treatment, and the decreases in the observation group were more obvious than those in the control group, with statistically significant differnce (P<0.05). The low-density lipoprotein cholesterol (LDL-C), triglyceride (TG), total cholesterol (TC) levels after treatment in the two groups were sig-nificantly lower than those before treatment, and the decrease in the observation group were more obvious (P<0.05). The two groups showed no significant adverse reactions during treatment. Conclusion The curative effect of traditional Chi-nese medicine combined with western medicine in the treatment of diabetic cerebral infarction is significant. It can improve the hemorheology and blood lipid levels, lower blood sugar, with no significant adverse reactions.
