CAJ | 학술논문

目的：探讨血栓抽吸术对急性ST段抬高型心肌梗死（STEMI）介入治疗患者左心室功能的改善作用。方法：选取STEMI介入治疗患者132例，采用随机数字表法将患者分为观察组（n=68，PCI介入联合血栓抽吸术）和对照组（n=64，PCI介入治疗），比较两组临床疗效和左心室功能指标的差异。结果：观察组TIMI血流1级率明显低于对照组， TIMI血流3级率明显高于对照组（P＜0.05）；观察组cTn-I峰值、cTn-I达峰时间和术后1 d NT-proBNP水平均明显低于对照组（P＜0.05）；观察组术后6个月LVEDV、LVESV明显低于对照组，LVEF明显高于对照组（P＜0.05）；两组术后6个月主要不良心血管事件发生率比较差异无统计学意义（P＞0.05）。结论：血栓抽吸术通过改善STEMI介入治疗患者心肌灌注和心肌酶指标水平从而显著改善左心室功能。
목적：탐토혈전추흡술대급성ST단태고형심기경사（STEMI）개입치료환자좌심실공능적개선작용。방법：선취STEMI개입치료환자132례，채용수궤수자표법장환자분위관찰조（n=68，PCI개입연합혈전추흡술）화대조조（n=64，PCI개입치료），비교량조림상료효화좌심실공능지표적차이。결과：관찰조TIMI혈류1급솔명현저우대조조， TIMI혈류3급솔명현고우대조조（P＜0.05）；관찰조cTn-I봉치、cTn-I체봉시간화술후1 d NT-proBNP수평균명현저우대조조（P＜0.05）；관찰조술후6개월LVEDV、LVESV명현저우대조조，LVEF명현고우대조조（P＜0.05）；량조술후6개월주요불양심혈관사건발생솔비교차이무통계학의의（P＞0.05）。결론：혈전추흡술통과개선STEMI개입치료환자심기관주화심기매지표수평종이현저개선좌심실공능。
Objective: To investigate the effect of thrombus aspiration on left ventricular function in the patients treated with STEMI interventiona.Methods:One hundred and thirty-two cases of patients were selected and randomly divided into an observation group (n=68, received PCI intervention combined with thrombus aspiration therapy) and a control group (n=64, received PCI interventional therapy only). The differences of the clinical efifcacy and the index of left ventricular function were compared between two groups.Results:The lfow rate of TIMI grade 1 was signiifcantly lower while the lfow rate of grade 3 higher in the observation group than in the control group (P<0.05). The value and appearing time of cTn-I peak, and NT-proBNP level at one day after operation were signiifcantly lower in the observation group than in the control group (P<0.05). The LVEDV and LVESV were signiifcantly lower and the LVEF was signiifcantly higher in the observation group than in the control group 6 months after the operation (P<0.05) and meanwhile there was no significant difference in the incidence of major adverse cardiovascular events between two groups. (P>0.05).Conclusion:Theindexes of myocardial perfusion and myocardial enzyme in the patients treated with STEMI interventiona and the left ventricular function can be improved by thrombus aspiration.