CAJ | 학술논문

1例41岁男性患者，因肿瘤化疗后粒细胞缺乏并发热被诊断为真菌感染，使用常规抗真菌药物疗效不佳，换用两性霉素B治疗过程中出现少见以胆红素升高为主的淤胆型肝功能损害。临床药师协助医师调整抗真菌治疗方案，并酌情给予保肝治疗后，患者感染控制，肝功能完全恢复，顺利出院。
1례41세남성환자，인종류화료후립세포결핍병발열피진단위진균감염，사용상규항진균약물료효불가，환용량성매소B치료과정중출현소견이담홍소승고위주적어담형간공능손해。림상약사협조의사조정항진균치료방안，병작정급여보간치료후，환자감염공제，간공능완전회복，순리출원。
Liver injury appeared rarely in the process of amphotericin B antifungal treatment in a 41 years old man because of fungal infection and fever after tumor chemotherapy and poor curative effect was observed when conventional antifungal agents were used. Clinical pharmacist assisted physician to adjust antifungal treatment and meanwhile a treatment for liver protection was adopted in the course of treatment. As a result, the liver injury was cured and the patient was discharged from hospital.