CAJ | 학술논문

目的：研究小儿呼吸道合胞病毒（RSV）肺炎的中医辨证分型规律、证候出现频数及不同中医证型与C 反应蛋白、肌酸激酶同工酶等指标的关系。方法通过对146例 RSV 肺炎患儿的病例四诊资料的回顾性分析，建立中医证候信息数据库，检测相关指标，探讨其与中医证型分布规律的相关性。结果146例 RSV 肺炎以风热闭肺、毒热闭肺、痰热闭肺居多，占90.42%；证候出现概率以咳嗽、气促、气喘、痰鸣最高，频率达80.14%；风热闭肺型病程天数明显短于痰热闭肺型和毒热闭肺型（P ＜0.01）；毒热闭肺型患儿年龄明显小于其他证型患儿年龄（P ＜0.01）；C 反应蛋白数值，痰热闭肺型高于风热闭肺型（P ＜0.05），毒热闭肺型与风热闭肺型比较，P ＜0.01；肌酸激酶同工酶数值，毒热闭肺型高于风热闭肺型（P ＜0.01）。结论146例合胞病毒肺炎主要以风热闭肺、毒热闭肺、痰热闭肺型最为常见，微观实验室检查与中医证候存在关联。
목적：연구소인호흡도합포병독（RSV）폐염적중의변증분형규률、증후출현빈수급불동중의증형여C 반응단백、기산격매동공매등지표적관계。방법통과대146례 RSV 폐염환인적병례사진자료적회고성분석，건립중의증후신식수거고，검측상관지표，탐토기여중의증형분포규률적상관성。결과146례 RSV 폐염이풍열폐폐、독열폐폐、담열폐폐거다，점90.42%；증후출현개솔이해수、기촉、기천、담명최고，빈솔체80.14%；풍열폐폐형병정천수명현단우담열폐폐형화독열폐폐형（P ＜0.01）；독열폐폐형환인년령명현소우기타증형환인년령（P ＜0.01）；C 반응단백수치，담열폐폐형고우풍열폐폐형（P ＜0.05），독열폐폐형여풍열폐폐형비교，P ＜0.01；기산격매동공매수치，독열폐폐형고우풍열폐폐형（P ＜0.01）。결론146례합포병독폐염주요이풍열폐폐、독열폐폐、담열폐폐형최위상견，미관실험실검사여중의증후존재관련。
Objective To study the syndromes distribution regularity of children with RSV Pneumonia,symptoms appear frequency and the correlation between TCM syndrome types of RSV pneumonia and C-reactive protein level,creatine ki-nase isoenzyme MB. Methods Retrospective analysis of 146 cases of children with RSV pneumonia with four TCM diag-nostics data was carried out to establish an information databases of syndromes,to detect Relevant indicators,searching for the relationship among indicators and syndrome. Results The 146 cases of RSV pneumonia was mostly in phlegm-heat blocking the lung syndrome,wind-heat blocking the lung syndrome and toxic-heat blocking the lung syndrome,ac-counting for 90. 42% ;Cough,shortness of breath is higher in symptoms appear frequency,to 80. 14% ;The average dura-tion of wind-heat blocking the lung syndrome was shorter than those phlegm-heat blocking the lung syndrome (P <0. 01);an average age of toxic-heat blocking the lung syndrome was less than those syndrome(P <0. 01);C-reac-tive protein values,phlegm heat type lung numerical closed on the high side,compared with wind-heat closed type lung syndrome(P <0. 05),toxic-heat closed type lung syndrome compared with wind-heat closed type lung syndrome(P <0. 01);CK-MB lever was higher in toxic-heat blocking the lung syndrome than wind-heat blocking the lung syndrome(P<0. 01). Conclusion The 146 cases of children with RSV pneumonia were mainly focused on wind-heat blocking the lung syndrome,toxic-heat blocking the lung syndrome and phlegm-heat blocking the lung syndrome,there were associa-tion between the micro laboratory examination and TCM syndrome.