CAJ | 학술논문

脑卒中是当前严重危害人类健康的疾病之一，包括缺血性卒中和出血性卒中两大类。有些药物可导致血黏度增高，具有潜在缺血性卒中的风险；而作为治疗心脑血管疾病的重要药物，抗血小板和抗凝药物本身亦增加了患者颅内出血及死亡的风险。据此，本文提出药物相关性卒中的概念，并探讨患者在使用相关药物期间的颅内出血风险及需接受神经外科手术时的围术期处理方案，旨在引起临床医师对药物相关性卒中的重视，为临床治疗提供指导和依据。
뇌졸중시당전엄중위해인류건강적질병지일，포괄결혈성졸중화출혈성졸중량대류。유사약물가도치혈점도증고，구유잠재결혈성졸중적풍험；이작위치료심뇌혈관질병적중요약물，항혈소판화항응약물본신역증가료환자로내출혈급사망적풍험。거차，본문제출약물상관성졸중적개념，병탐토환자재사용상관약물기간적로내출혈풍험급수접수신경외과수술시적위술기처리방안，지재인기림상의사대약물상관성졸중적중시，위림상치료제공지도화의거。
Stroke classified into ischemic and hemorrhagic subtypes, is among the most devastating diseases for human being.Certain drugs could increase the blood viscosity, thereby increasing the potential risk of ischemia.Anti-platelet and anti-coagulation drugs, as the treatment of first choice, increase the risk of intracranial hemorrhage and death.Here, we are the first to propose the concept of drug-related stroke, and discuss the treatment strategy for patients who are complicated with intracranial hemorrhage or plan to receive neurosurgical operation during either anti-platelet or anti-coagulation medication.We hope to arouse the attention for drug related stroke among the clinicians and offer recommendation for clinical intervention.