CAJ | 학술논문

目的：探讨肾小球滤过率测定对早期糖尿病肾病患者治疗的作用。方法选取2012年1月～2014年1月我院收治的早期糖尿病肾病患者以及在此期间来我院进行体检的正常人为研究对象。分为早期糖尿病组与正常组，每组各30例；同时对两组进行肾小球滤过率测定，比较两组的肾小球滤过率。结果正常白蛋白尿组、微量白蛋白尿组的GFR高于正常组平均指标，且两者与正常组相比差异有统计学意义（P＜0.05）；大量白蛋白尿组的GFR指标低于正常组，两者相比差异有统计学意义（P＜0.05）；随UAER的增多，糖尿病患者的BUN、Cr升高，且只有大量白蛋白尿组患者的BUN、Cr与正常组相比差异有统计学意义（P＜0.05）。结论利用肾小球滤过率测定对早期糖尿病患者进行检查，其结果可以准确反映早期糖尿病肾病患者的肾损害状况，从而为临床治疗提供参考，因此值得临床推广应用。
목적：탐토신소구려과솔측정대조기당뇨병신병환자치료적작용。방법선취2012년1월～2014년1월아원수치적조기당뇨병신병환자이급재차기간래아원진행체검적정상인위연구대상。분위조기당뇨병조여정상조，매조각30례；동시대량조진행신소구려과솔측정，비교량조적신소구려과솔。결과정상백단백뇨조、미량백단백뇨조적GFR고우정상조평균지표，차량자여정상조상비차이유통계학의의（P＜0.05）；대량백단백뇨조적GFR지표저우정상조，량자상비차이유통계학의의（P＜0.05）；수UAER적증다，당뇨병환자적BUN、Cr승고，차지유대량백단백뇨조환자적BUN、Cr여정상조상비차이유통계학의의（P＜0.05）。결론이용신소구려과솔측정대조기당뇨병환자진행검사，기결과가이준학반영조기당뇨병신병환자적신손해상황，종이위림상치료제공삼고，인차치득림상추엄응용。
Objective To investigate the effect of the determination of glomerular filtration rate in treatment of early diabetic nephropathy.Methods Patients with early diabetic nephropathy and normal in our hospital from January 2012 to January 2014 were selected as a medical study,and divided into an early diabetes group and a normal group,30 cases in each group.The glomerular filtration rate between the two groups were determined and compared. Results GFR average index in normal albuminuria group and microalbuminuria group was higher than that in normal group, and difference in the two group compared with the normal group was significant (P<0.05);A large number of albuminuria GFR index was lower than that in the normal group,with significant difference (P<0.05);With UAER,diabetic patients with elevated BUN,Cr,and only a large number of albuminuria group of patients with BUN,Cr significant difference compared with the normal group (P<0.05). Conclusion Using the determination of glomerular filtration rate for early check in diabetic patients,the result can accurately reflect the status of early diabetic nephropathy in patients with renal damage,so as to provide reference for clinical treatment,is worthy of clinical application.