中华行为医学与脑科学杂志
中華行為醫學與腦科學雜誌
중화행위의학여뇌과학잡지
Chinese Journal of Behavioral Medicine and Brain Science
2015年
10期
892-895
,共4页
李雪%朱幼玲%席春华%董斌%张婷婷%翟登月%唐敏
李雪%硃幼玲%席春華%董斌%張婷婷%翟登月%唐敏
리설%주유령%석춘화%동빈%장정정%적등월%당민
原发性失眠%情绪%记忆%神经心理学测试
原髮性失眠%情緒%記憶%神經心理學測試
원발성실면%정서%기억%신경심이학측시
Primary insomnia%Emotions%Memory%Neuropsychological tests
目的 了解原发性失眠(primary insomnia,PI)患者情绪记忆的改变,初步探讨不同情绪效价对P1患者的记忆影响模式.方法 使用不同效价的情绪图片学习-再认任务分别对30名PI患者(PI组)和20名健康对照组(HC组)进行情绪记忆测试.结果 在学习阶段,PI组的情绪图片评分成绩(分别为:正性(11.30±3.75)分;中性(11.47±3.21)分;负性(11.43±4.12)分)与HC组相比(正性(11.60±4.00)分,中性(11.05±3.73)分,负性(12.60±2.06)分),差异无统计学意义(均P＞0.05).在再认阶段,PI组总情绪图片再认正确得分较HC组明显下降[分别为:(39.40±6.43)分和(43.40±4.88)分],差异有统计学意义(P＜0.05).PI组对不同效价情绪图片再认存在分离现象,相对于正常对照组,PI组在正性情绪图片再认人[分别为PI组:(12.60±2.42)分;HC组:(14.05±2.19)分]和中性情绪图片再认[分别为PI组:(12.87±3.18)分;HC组:(14.75±1.80)分]正确得分明显下降,差异有统计学意义(均P＜0.05);而两组负性情绪效价图片的再认正确得分[分别为PI组:(13.93±1.76)分;HC组:(14.70±1.59)分]的差异无统计学意义(P＞0.05).结论 PI患者存在情绪记忆的损害,主要表现为正性、中性情绪记忆受损,而负性情绪记忆相对保留,提示PI对不同效价情绪记忆的影响可能依赖不同的神经机制.
目的 瞭解原髮性失眠(primary insomnia,PI)患者情緒記憶的改變,初步探討不同情緒效價對P1患者的記憶影響模式.方法 使用不同效價的情緒圖片學習-再認任務分彆對30名PI患者(PI組)和20名健康對照組(HC組)進行情緒記憶測試.結果 在學習階段,PI組的情緒圖片評分成績(分彆為:正性(11.30±3.75)分;中性(11.47±3.21)分;負性(11.43±4.12)分)與HC組相比(正性(11.60±4.00)分,中性(11.05±3.73)分,負性(12.60±2.06)分),差異無統計學意義(均P＞0.05).在再認階段,PI組總情緒圖片再認正確得分較HC組明顯下降[分彆為:(39.40±6.43)分和(43.40±4.88)分],差異有統計學意義(P＜0.05).PI組對不同效價情緒圖片再認存在分離現象,相對于正常對照組,PI組在正性情緒圖片再認人[分彆為PI組:(12.60±2.42)分;HC組:(14.05±2.19)分]和中性情緒圖片再認[分彆為PI組:(12.87±3.18)分;HC組:(14.75±1.80)分]正確得分明顯下降,差異有統計學意義(均P＜0.05);而兩組負性情緒效價圖片的再認正確得分[分彆為PI組:(13.93±1.76)分;HC組:(14.70±1.59)分]的差異無統計學意義(P＞0.05).結論 PI患者存在情緒記憶的損害,主要錶現為正性、中性情緒記憶受損,而負性情緒記憶相對保留,提示PI對不同效價情緒記憶的影響可能依賴不同的神經機製.
목적 료해원발성실면(primary insomnia,PI)환자정서기억적개변,초보탐토불동정서효개대P1환자적기억영향모식.방법 사용불동효개적정서도편학습-재인임무분별대30명PI환자(PI조)화20명건강대조조(HC조)진행정서기억측시.결과 재학습계단,PI조적정서도편평분성적(분별위:정성(11.30±3.75)분;중성(11.47±3.21)분;부성(11.43±4.12)분)여HC조상비(정성(11.60±4.00)분,중성(11.05±3.73)분,부성(12.60±2.06)분),차이무통계학의의(균P＞0.05).재재인계단,PI조총정서도편재인정학득분교HC조명현하강[분별위:(39.40±6.43)분화(43.40±4.88)분],차이유통계학의의(P＜0.05).PI조대불동효개정서도편재인존재분리현상,상대우정상대조조,PI조재정성정서도편재인인[분별위PI조:(12.60±2.42)분;HC조:(14.05±2.19)분]화중성정서도편재인[분별위PI조:(12.87±3.18)분;HC조:(14.75±1.80)분]정학득분명현하강,차이유통계학의의(균P＜0.05);이량조부성정서효개도편적재인정학득분[분별위PI조:(13.93±1.76)분;HC조:(14.70±1.59)분]적차이무통계학의의(P＞0.05).결론 PI환자존재정서기억적손해,주요표현위정성、중성정서기억수손,이부성정서기억상대보류,제시PI대불동효개정서기억적영향가능의뢰불동적신경궤제.
Objective To investigate the emotional memory impairment in patients with primary insomnia (PI) and explore the neurobiological mechanisms underlying primary insomnia through emotional memory tasks involving different valance of emotional pictures.Methods Thirty patients with primary insomnia(PI group) and twenty healthy controls(HC group) were given emotional memory tasks using positive,neutral and negative valence images.The emotional memory was evaluated by the recognition of emotional pictures.Results Compared with healthy controls (positive (11.60±4.00) , neutral (11.05± 3.73) and negative (12.60± 2.06) , respectively), patients with PI (positive (11.30±3.75),neutral (11.47±3.21) and negative (11.43±4.12) ,respectively) showed no significant difference in appraisal of the emotional pictures (P＞0.05).Compared with healthy controls (43.40± 4.88) for the emotional images memorizing task,patients with PI (39.40±6.43) exhibited evident deficit of all emotional images (P＜0.05).Furthermore, the accuracy in recognizing both positive (12.60± 2.42) and neutral (12.87±3.18) valence pictures were significantly lower in patients with P1 than those in healthy controls(positive (14.05±2.19) and neutral (14.75± 1.80)) (P＜0.05).There was no significant difference in negative stimulus between PI group(13.93±1.76) and HC group(14.70±1.59) (P＞0.05).Conclusion The results suggest thant emotional memory is impaired in patients with PI.Moreover,the emotional memory for positive and neutral vanlence pictures is impaired but the emotional memory for negative is relatively spared in patients with primary insomnia.The results also indicate that impaired emotional memory with different valences may relate with distinct neuromechanisms.
