CAJ | 학술논문

目的探讨注意缺陷多动障碍(attention-deficit/hyperactivity disorder,ADHD)患儿不同阈值的工作记忆.方法研究采用35例ADHD儿童及与其人口学资料相匹配的33名健康儿童;采用不同反应时的N-back任务测量工作记忆.结果 ADHD组在阈下2-back任务中的错误数[(4.49±1.20)次]显著高于对照组[(3.79±1.14)次],差异有统计学意义(t=-2.459,P=0.017).ADHD组在阈下1-back任务的错误数及2-back任务反应时[(4.77±1.09)次;(1 447.49±271.35) ms]均差于阈上刺激[(3.09±1.63)次;(1 315.48±229.63) ms],差异有统计学意义(t=4.755,P=0.000;t=-2.281,P=0.029),而对照组差异无统计学意义(P＞0.05).结论 ADHD儿童工作记忆功能存在损伤.
목적 탐토주의결함다동장애(attention-deficit/hyperactivity disorder,ADHD)환인불동역치적공작기억.방법 연구채용35례ADHD인동급여기인구학자료상필배적33명건강인동;채용불동반응시적N-back임무측량공작기억.결과 ADHD조재역하2-back임무중적착오수[(4.49±1.20)차]현저고우대조조[(3.79±1.14)차],차이유통계학의의(t=-2.459,P=0.017).ADHD조재역하1-back임무적착오수급2-back임무반응시[(4.77±1.09)차;(1 447.49±271.35) ms]균차우역상자격[(3.09±1.63)차;(1 315.48±229.63) ms],차이유통계학의의(t=4.755,P=0.000;t=-2.281,P=0.029),이대조조차이무통계학의의(P＞0.05).결론 ADHD인동공작기억공능존재손상.
Objective To explore the mechanisms underlying supraliminal and subliminal N-back task in the children with symptoms of attention-deficit/hyperactivity disorder (ADHD).Methods Thirty-five ADHD children and thirty-three matched normal controls were enrolled.Working memory was measured with the different reaction time of N-back task.Results The error number of the subliminal 2-back task in ADHD group ((4.49± 1.20) times) was worse than that of the healthy controls ((3.79±-1.14) times), and the difference was significant(t=-2.459, P=0.017).In ADHD group,the error number of 1-back task and reaction time of 2-back task in subliminal task ((4.77±1.09) times, (1 447.49±271.35) ms) were worse than those of supraliminal task ((3.09± 1.63) times, (1 315.48±229.63) ms), and the difference was significant between the two tasks (t=4.755, P=0.000;t=-2.281, P=0.029).But there were no significant findings in healthy controls(P＞0.05).Conclusion The present study suggests that the working memory is impaired in ADHD children.