中国卫生标准管理
中國衛生標準管理
중국위생표준관리
China Health Standard Management
2015年
27期
140-141
,共2页
心血管疾病%超氧化物歧化酶%同型半胱氨酸
心血管疾病%超氧化物歧化酶%同型半胱氨痠
심혈관질병%초양화물기화매%동형반광안산
Cardiovascular disease%Superoxide dismutase%Homocysteine
目的 探讨血清超氧化物歧化酶(SOD)和同型半胱氨酸(HCY)水平与心血管疾病的相关性.方法 选取我院100例心血管病患者,按照疾病类型分为急性冠状动脉综合征(ACS)组、不稳定型心绞痛(UAP)组、动脉粥样硬化(AS)组,另选取同期体检健康者50例作为健康对照组,测定所有研究对象的血清SOD和HCY水平,并进行相关性分析.结果 3种心血管疾病患者的血清SOD水平低于健康对照组, HCY水平高于健康对照组,差异均有统计学意义(P<0.05),与治疗前比较,ACS组与AS组患者治疗后血清SOD水平均升高,HCY水平均下降,差异均有统计学意义(P<0.05),且ACS组及AS组患者血清SOD与HCY水平均呈负相关(相关系数r 分别为0.901、0.924, P<0.05).结论 血清SOD和HCY水平检测对ASC与AS的治疗和预后有重要的临床指导价值.
目的 探討血清超氧化物歧化酶(SOD)和同型半胱氨痠(HCY)水平與心血管疾病的相關性.方法 選取我院100例心血管病患者,按照疾病類型分為急性冠狀動脈綜閤徵(ACS)組、不穩定型心絞痛(UAP)組、動脈粥樣硬化(AS)組,另選取同期體檢健康者50例作為健康對照組,測定所有研究對象的血清SOD和HCY水平,併進行相關性分析.結果 3種心血管疾病患者的血清SOD水平低于健康對照組, HCY水平高于健康對照組,差異均有統計學意義(P<0.05),與治療前比較,ACS組與AS組患者治療後血清SOD水平均升高,HCY水平均下降,差異均有統計學意義(P<0.05),且ACS組及AS組患者血清SOD與HCY水平均呈負相關(相關繫數r 分彆為0.901、0.924, P<0.05).結論 血清SOD和HCY水平檢測對ASC與AS的治療和預後有重要的臨床指導價值.
목적 탐토혈청초양화물기화매(SOD)화동형반광안산(HCY)수평여심혈관질병적상관성.방법 선취아원100례심혈관병환자,안조질병류형분위급성관상동맥종합정(ACS)조、불은정형심교통(UAP)조、동맥죽양경화(AS)조,령선취동기체검건강자50례작위건강대조조,측정소유연구대상적혈청SOD화HCY수평,병진행상관성분석.결과 3충심혈관질병환자적혈청SOD수평저우건강대조조, HCY수평고우건강대조조,차이균유통계학의의(P<0.05),여치료전비교,ACS조여AS조환자치료후혈청SOD수평균승고,HCY수평균하강,차이균유통계학의의(P<0.05),차ACS조급AS조환자혈청SOD여HCY수평균정부상관(상관계수r 분별위0.901、0.924, P<0.05).결론 혈청SOD화HCY수평검측대ASC여AS적치료화예후유중요적림상지도개치.
Objective To explore the correlation between the levels of serum homocysteine(HCY)and superoxide dismutase(SOD)with cardiovascular diseases.Methods 100 patients with cardiovascular diseases were selected and divided into the acute coronary syndrome(ACS)group ,unstable angina pectoris (UAP)group and the atherosclerosis(AS)group according to the disease types,contemporaneous 50 individuals of healthy physical examination were selected as the healthy control group ,the serum SOD and HCY levels were detected in al the research subjects and the correlation was analyzed. Results The serum SOD level in the 3 cardiovascular disease groups was significant lower than that in the healthy control group,while the HCY level was higher than that in the healthy control group,the diferences between them had statistical significance(P<0.05). Compared with those before treatment,the serum SOD levels after treatment in the ACS group and the AS group were significant increased and the serum HCY levels were significant decreased with statistical diferences(P<0.05), moreover serum SOD and HCY levels showed the negative correlation in the ACS group and the AS group(r=0.901、0.924,P<0.05).Conclusion Detecting serum SOD and HCY levels could have an important guidance value to the treatment and prognosis of ACS and AS .
